Deck 9: The Hematopoietic and Lymphoid Systems

Question 1

Macrocytic,megaloblastic anemia occurs typically in association with:

A) Chronic dermatitis
B) Atrophic gastritis
C) Hypothyroidism
D) Old age
E) Chronic osteoarthritis

Answer 1

Atrophic gastritis

Question 2

All of the following are hemolytic anemias caused by red blood cell abnormalities (intracorpuscular defects)except:

A) Sickle cell anemia
B) Hereditary spherocytosis
C) Thalassemia major
D) Thalassemia minor
E) Autoimmune hemolytic anemia

Answer 2

Autoimmune hemolytic anemia

Question 3

The sickling of red blood cells of patients with sickle cell anemia can be induced in vitro by adding:

A) Normal blood
B) Normal serum
C) Oxygen
D) An oxygen-binding chemical such as metabisulfite
E) Alkali

Answer 3

An oxygen-binding chemical such as metabisulfite

Question 4

Fibrin split products are typically found in the urine of patients who have:

A) Hemophilia A
B) Hemophilia B
C) Disseminated intravascular coagulation (DIC)
D) Aplastic anemia
E) Thrombocytopenia

Question 5

The diagnostic feature of multiple myeloma is best documented by:

A) Peripheral blood smear analysis
B) Serum electrophoresis
C) Measurement of serum osmolarity
D) Measurement of serum calcium
E) Molecular biology

Question 6

Which of the following lymphomas is classified as a low-grade lymphoma?

A) Follicular lymphoma
B) Diffuse large-cell lymphoma
C) Burkitt's lymphoma
D) Immunoblastic lymphoma
E) Lymphoblastic lymphoma

Question 7

Which virus is a proven cause of leukemia/lymphoma in humans?

A) Epstein-Barr virus
B) HIV
C) HTLV-1
D) HPV
E) CMV

Question 8

Punched-out bone lesions of the calvaria seen by x-ray examination are typical of:

A) Hodgkin's disease
B) Thrombotic thrombocytopenic purpura
C) Multiple myeloma
D) Aplastic anemia
E) Lymphocytic lymphoma

Question 9

Sickle cell hemoglobin is routinely identified in the laboratory by:

A) Polarized light microscopy
B) Electron microscopy
C) Electrophoresis
D) Immunochemistry
E) Electron spin microscopy

Question 10

Which of the following leukemias has the best prognosis without chemotherapy?

A) Acute lymphoblastic leukemia
B) Acute myelogenous leukemia
C) Chronic lymphocytic leukemia
D) Chronic myelogenous leukemia
E) Plasma cell leukemia

Question 11

Epstein-Barr virus,a possible cause of Burkitt's lymphoma,has a predilection for infecting:

A) T-suppressor/cytotoxic lymphocytes
B) T-helper lymphocytes
C) Plasma cells
D) B lymphocytes
E) Eosinophils

Question 12

Consumption of platelets associated with widespread hemorrhages is a feature of:

A) Hemophilia A
B) Hemophilia B
C) Aplastic anemia
D) Leukemia
E) Disseminated intravascular coagulation (DIC)

Question 13

Overall,the most common form of leukemia is:

A) Acute lymphoblastic leukemia
B) Acute myelogenous leukemia
C) Chronic lymphocytic leukemia
D) Chronic myelogenous leukemia
E) Plasma cell leukemia

Question 14

The most common form of leukemia in children younger than the age of 5 years is:

A) Acute lymphoblastic leukemia
B) Acute myelogenous leukemia
C) Chronic lymphocytic leukemia
D) Chronic myelogenous leukemia
E) Plasma cell leukemia

Question 15

The most common symptom of lymphomas is:

A) Lymph node enlargement
B) Infection
C) Fever
D) Pruritus
E) Sweating

Question 16

Aplastic anemia is most often:

A) Idiopathic
B) Secondary to viral infection
C) Radiation induced
D) Drug induced
E) Immune mediated

Question 17

All the following findings are typical of secondary polycythemia except:

A) Increased number of red blood cells in circulation
B) Hyperviscosity of the blood
C) Increased number of erythroid precursors in the bone marrow
D) Increased incidence of thrombi
E) Association with myelodysplastic syndromes

Question 18

Thalassemia minor is a disease involving the gene that encodes:

A) Globin chains of hemoglobin
B) The heme portion of hemoglobin
C) The iron-binding portion of hemoglobin
D) The porphyrin ring of hemoglobin
E) Bilirubin synthetase

Question 19

Microcytic hypochromic anemia with low hemosiderin stores in the bone marrow will respond favorably to treatment with:

A) Vitamin C
B) Vitamin B₁2
C) Folic acid
D) Iron
E) Selenium