Deck 23: Skin

Question 1

Which of the following skin lesions becomes darker and more pigmented upon exposure to sunlight?

A) Vitiligo
B) Lentigo
C) Ephelis
D) Congenital melanocytic nevus
E) Dysplastic nevus

Answer 1

Ephelis

Question 2

Which of the following skin lesions will most likely progress to invasive squamous cell carcinoma?

A) Actinic keratosis
B) Seborrheic keratosis
C) Seborrheic dermatitis
D) Epidermal inclusion cyst
E) Steatocystoma multiplex

Answer 2

Actinic keratosis

Question 3

A well-demarcated, coin-like, dark brown lesion appeared on the shoulder of a 59-year-old man. The lesion appears velvety, greasy, and has a "stuck on" appearance so that it can easily be removed. Which of the following is the most likely diagnosis?

A) Lentigo
B) Ephelis
C) Vitiligo
D) Seborrheic keratosis
E) Actinic keratosis

Answer 3

Seborrheic keratosis

Question 4

Basal cell carcinoma of the skin often contains mutations of the p53 gene and the gene called PTCH (mutated in congenital nevoid basal cell carcinoma syndrome). These mutations are most likely the result of action of which of the following?

A) Epidermal growth factor
B) G-protein signal transduction system
C) Chemical carcinogens from the environment
D) Ultraviolet light
E) Cosmic radiation