Deck 9: Inflammation and Immunity

Question 1

Functions of T cells include

A) synthesizing antibodies.
B) secreting cytokines.
C) killing antigen-presenting cells.
D) stimulating of B cells.
E) killing virally infected cells.

Answer 1

secreting cytokines.
killing antigen-presenting cells.
stimulating of B cells.
killing virally infected cells.

Question 2

The primary function of kinins is

A) phagocytosis of antigens.
B) production of antibodies.
C) to limit immune reactions.
D) vasodilation to enhance inflammation.

Answer 2

vasodilation to enhance inflammation.

Question 3

Interleukin-1, interleukin-6, and tumor necrosis factor-a are inflammatory cytokines secreted by

A) plasma cells.
B) neutrophils.
C) lymphocytes.
D) macrophages.

Answer 3

macrophages.

Question 4

Leukocytosis with a "shift to the left" refers to

A) elevated segmented neutrophils.
B) elevated immature neutrophils.
C) decreased monocytes.
D) decreased immature neutrophils.

Question 5

Active immunity involves

A) injection of preformed human antibodies.
B) injection of human immune globulin.
C) injection with preformed animal antibodies.
D) vaccines with dead or altered organisms.
E) active infections.

Question 6

Passive immunity is provided by

A) transfer of preformed human antibodies.
B) injection of human immune globulin.
C) injection with preformed animal antibodies.
D) vaccines with dead or altered organisms.
E) active infections.

Question 7

The mononuclear phagocyte system consists of

A) monocytes and tissue macrophages.
B) dendritic cells.
C) bone marrow stem cells.
D) antibody-secreting plasma cells.
E) basophils.

Question 8

Characteristics of complement include

A) stimulating chemotaxis.
B) lysing target cells.
C) having multiple plasma proteins.
D) being synthesized in the bone marrow.
E) enhancing phagocytosis.

Question 9

Functions of antibodies include

A) antigen agglutination.
B) antigen precipitation.
C) opsonization.
D) phagocytosis.
E) complement activation.

Question 10

The primary function of eosinophils is to

A) kill parasitic helminths (worms).
B) kill bacteria.
C) stop viral replication.
D) phagocytize fungi.

Question 11

Which clinical finding is most indicative of an acute bacterial infection?

A) Increased (band) neutrophils.
B) Elevated temperature.
C) Elevated erythrocyte sedimentation rate.
D) Elevated WBC count.

Question 12

Immunity to a specific organism can be determined by

A) active phase protein count.
B) antibody titer.
C) erythrocyte sedimentation rate.
D) WBC count.

Question 13

Antigen-presenting cells function to

A) display foreign antigen on their cell surfaces bound to MHC.
B) stimulate cytokine production by macrophages.
C) phagocytose and degrade foreign antigens.
D) initiate the complement cascade by way of the alternative pathway.

Question 14

The "classical pathway" for activation of the complement cascade is triggered by

A) activation of C3.
B) inflammation.
C) first recognition of an antigen.
D) antigen-antibody complexes.

Question 15

Functions of B cells include

A) synthesizing antibodies.
B) secreting cytokines.
C) killing antigen-presenting cells.
D) stimulating B cells.
E) killing virally infected cells.

Question 16

The spleen is an important defense against infection, because it

A) activates the complement cascade.
B) initiates inflammation.
C) controls phagocytosis.
D) filters the blood.

Question 17

Activation of the complement cascade results in

A) antibody production.
B) inflammation.
C) immunosuppression.
D) autoimmunity.
E) chemotaxis.

Question 18

The membrane attack complex formed by complement is similar in function to

A) CD4⁺.
B) granzymes.
C) gp120.
D) perforin.

Question 19

Proteins that are increased in the bloodstream during acute inflammation are called

A) membrane attack complexes.
B) selectin receptors.
C) acute phase proteins.
D) major histocompatibility complexes.