Deck 10: Alterations in Immune Function

Question 1

Seasonal allergic rhinitis is most involved in type ____ hypersensitivity reactions.

Answer 1

I
Seasonal allergic rhinitis is most involved in type I hypersensitivity reactions.

Question 2

Patients with immunodeficiency disorders are usually first identified because they

A) run high fevers.
B) have unusually high WBC counts.
C) develop brain infections.
D) develop recurrent infections.

Answer 2

develop recurrent infections.

Question 3

RhoGAM (an Rh antibody)would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.

A) negative; positive; positive
B) positive; negative; negative
C) negative; negative; positive
D) negative; negative; negative

Answer 3

negative; negative; positive

Question 4

Severe combined immunodeficiency (SCID)syndrome is an example of a(n)

A) deficient immune response.
B) excessive immune response.
C) primary acquired immunodeficiency.
D) hypersensitivity reaction.

Question 5

The effects of histamine release include

A) vasoconstriction.
B) bronchodilation.
C) increased vascular permeability.
D) decreased gut permeability.

Question 6

An important mediator of a type I hypersensitivity reaction is

A) complement.
B) antigen-antibody immune complexes.
C) T cells.
D) histamine.

Question 7

A child with a history of recent strep throat infection develops glomerulonephritis.This is most likely a type _____ hypersensitivity reaction.

A) I
B) II
C) III
D) IV

Question 8

The principle Ig mediator of type I hypersensitivity reactions is

A) IgA.
B) IgG.
C) IgM.
D) IgE.

Question 9

Secondary immune deficiency problems may be caused by

A) surgery.
B) high blood sugar.
C) corticosteroids.
D) genetic disorders.
E) low protein level.

Question 10

Transfusion reactions involve RBC destruction caused by

A) donor antigens.
B) recipient antibodies.
C) donor T cells.
D) recipient T cells.

Question 11

Certain autoimmune diseases are associated with the presence of specific proteins on a person's cells.These proteins are called ________ proteins.

A) complement
B) antibody receptor
C) HLA or MHC
D) TCR or BCR

Question 12

The hypersensitivity reaction that does not involve antibody production is type

A) I.
B) II.
C) III.
D) IV.

Question 13

Dramatic hypotension sometimes accompanies type I hypersensitivity reactions, because

A) massive histamine release from mast cells leads to vasodilation.
B) toxins released into the blood interfere with cardiac function.
C) anaphylaxis results in large volume losses secondary to sweating.
D) hypoxia due to bronchoconstriction impairs cardiac function.

Question 14

Which disorder is associated with a type III hypersensitivity mechanism of injury?

A) Systemic lupus erythematosus
B) Graves disease
C) Erythroblastosis fetalis
D) Seasonal allergic rhinitis

Question 15

The most common primary immune deficiency that affects only B cells is

A) DiGeorge.
B) Bruton agammaglobulinemia.
C) Wiskott-Aldrich.
D) selective IgA.

Question 16

Which disorder is considered a primary immunodeficiency disease?

A) HIV/AIDS
B) Malnutrition immunodeficiency
C) Cancer immunodeficiency
D) Radiation immunodeficiency

Question 17

Anaphylaxis may occur in certain hypersensitivity reactions, including type

A) I.
B) II.
C) III.
D) IV.

Question 18

A primary effector cell of the type I hypersensitivity response is

A) monocytes.
B) mast cells.
C) neutrophils.
D) cytotoxic cells.

Question 19

Myasthenia gravis is a type II hypersensitivity disorder that involves

A) impaired muscle function.
B) symptoms of hyperthyroidism.
C) symptoms of arthritis or polyarthralgia.
D) symptoms of glomerular disease.

Question 20

Autoimmune diseases result from

A) overactive immune function.
B) increase in self-tolerance.
C) failure of the immune system to differentiate self and nonself molecules.
D) communicable infections.