Deck 6: Other Blood Group Systems

Question 1

How many antigens are there in the Duffy blood group system?

A)3
B)6
C)8
D)9

Answer 1

6

Question 2

Antibodies in the Ii blood group system are usually

A)IgG alloantibodies that are detected when testing occurs at body temperature
B)IgG autoantibodies that are detected when testing occurs at room temperature
C)IgM alloantibodies that are detected when testing occurs at body temperature
D)IgM autoantibodies that are detected when testing occurs at room temperature

Answer 2

IgM autoantibodies that are detected when testing occurs at room temperature

Question 3

Detection of anti-i has been associated with

A)hemolytic disease of the fetus and newborn
B)infectious mononucleosis
C)paroxysmal cold hemoglobinuria
D)sickle cell anemia

Answer 3

infectious mononucleosis

Question 4

Which antibody commonly causes delayed hemolytic transfusion reactions?

A)Anti-A,B
B)Anti-Jkᵃ
C)Anti-K
D)Anti-Leᵃ

Question 5

The McLeod phenotype is very rare and is often associated with a hereditary form of

A)Chronic granulomatous disease (CGD)
B)Cold agglutinin syndrome (CAS)
C)Paroxysmal cold hemoglobinuria (PCH)
D)Paroxysmal nocturnal hemoglobinemia (PNH)

Question 6

Within the Knops blood group system,all of the following are high-incidence antigens except

A)Kna
B)McCa
C)McCb
D)Yka

Question 7

The antigens of the Chido/Rodgers system are located on the _____ complement component.

A)C1
B)C2
C)C3
D)C4

Question 8

The antigens of the Kell system are found on a ________ that passes through the red blood cell membrane.

A)glycogen
B)glycolipid
C)glycophorin
D)glycoprotein

Question 9

How many antigens are in the Kidd system?

A)3
B)9
C)12
D)19

Question 10

The full expression of Lewis antigens is not reached until around ___ years of age.

A)3
B)5
C)7
D)9

Question 11

Which of the following blood group systems has unknown clinical significance?

A)Yt
B)Scianna
C)Gill
D)Raph

Question 12

All GPI-linked glycoproteins are absent in individuals suffering from which condition?

A)Chronic granulomatous disease (CGD)
B)Hemolytic disease of the fetus and newborn (HDFN)
C)Paroxysmal cold hemoglobinuria (PCH)
D)Paroxysmal nocturnal hemoglobinemia (PNH)

Question 13

The most common chemical reagent used in North America to alter reagent red blood cells is the enzyme

A)bromelin
B)ficin
C)papain
D)trypsin

Question 14

Which antigens in the Lutheran system are not high-incidence antigens?

A)Auᵃ,Auᵇ,and Luᵃ
B)Auᵃ,Auᵇ,and Luᵇ
C)Luᵃ,Luᵇ,and AnWj
D)Luᵃ,Luᵇ,and Lu3

Question 15

The null phenotype in the Duffy system is produced by inheriting

A)the genotype Fyᵃ/Fyᵃ
B)the phenotype Fy (a+b-)
C)the FY3 antigen
D)two FY genes

Question 16

Regarding antigens in the Duffy system,all of the following statements are true except

A)Commonly encountered antigens include the allelic pair Fyᵃ and Fyᵇ.
B)Duffy antigens are well developed at birth.
C)Fy3 and Fy5 antigens are destroyed by treatment with ficin enzyme.
D)Fyx is a weak expression of the Fyᵇ antigen.

Question 17

How many antigens are in the Cartwright blood group system?

A)2
B)3
C)4
D)5

Question 18

The Xgᵃ antigen results from a gene on the ____ chromosome.

A)X
B)Y
C)XG
D)YG

Question 19

Which antigen is one of the antigens in the ISBT classification called Series 901?

A)Bga
B)Knb
C)Sda
D)Tcc

Question 20

A gene,XK,carried on the X chromosome results in production of the high-incidence antigen

A)Jsb
B)KEL
C)Kpb
D)Kx