Deck 4: Molecular Basis for Embryonic Development

Question 1

Which of the following families of transcription factors contain(s)a homeobox?

A)Lim
B)Pax
C)Msx
D)Dlx
E)All of the above

Answer 1

E

Question 2

Which Hox gene is expressed in the most anterior position in the embryonic body?

A)Hoxc-12
B)Hoxd-11
C)Hoxb-5
D)Hoxa-4
E)Hoxb-9

Answer 2

D

Question 3

Which molecule is most heavily involved in the process of lateral inhibition?

A)Sonic hedgehog
B)Sox-9
C)Notch
D)Transforming growth factor-β
E)None of the above

Answer 3

C

Question 4

Which family of genes is most heavily involved in segmentation of the body?

A)Hedgehog
B)Pax
C)Transforming growth factor-β
D)Fibroblast growth factor
E)Hox

Question 5

Which growth factor must be combined with cholesterol to be active?

A)Sonic hedgehog
B)Fibroblast growth factor-2
C)Transforming growth factor-β
D)Bone morphogenetic protein-7
E)None of the above

Question 6

Which of the following is/are properties of Hox genes?

A)Twelve paralogous groups
B)5′ genes expressed in more anterior structures than 3′ genes
C)Four clusters of Hox genes located on two chromosomes
D)Expressed in developing segmented structures
E)All of the above

Question 7

The products of homeobox-containing genes are _______________.

A)Extracellular matrix receptors
B)Cytoskeletal elements
C)Inductors
D)Transcription factors
E)Cell adhesion molecules

Question 8

β-Catenin is an integral part of which signaling/signal transduction pathway?

A)Fibroblast growth factor/receptor tyrosine kinase
B)Wnt
C)Delta-Notch
D)Transforming growth factor/serine-threonine kinase
E)None of the above

Question 9

Which of the following is not a family of growth factors?

A)Transforming growth factor
B)Wnt
C)Pax
D)Fibroblast growth factor
E)Hedgehog