Deck 14: Transfusion Therapy in Selected Patients

Question 1

Which of the following contributes to the high blood use in a liver transplant surgery?

A) The liver is a very large organ.
B) It is difficult to find close human leukocyte antigen matches for liver transplants.
C) Platelets are stored in the liver.
D) The liver produces the vitamin K-dependent coagulation factors.

Answer 1

D
The liver is essential in producing coagulation factors.

Question 2

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Decreases immunization to leukocytes

Answer 2

E

Question 3

Iron chelation should accompany red blood cell transfusion in which of the following?

A) Aplastic anemia
B) Autoimmune hemolytica anemia
C) Sickle cell anemia
D) Anemia caused by trauma

Answer 3

C
Iron chelation to prevent iron overload in sickle cell anemia is necessary to repeat red blood cell transfusion.

Question 4

Washed red blood cells would be the product of choice for a patient with:

A) multiple red cell antibodies.
B) hepatitis infection.
C) warm autoimmune disease.
D) anti-IgA antibodies.

Question 5

ABO-matched organ transplants are critical in all the following except:

A) bone marrow.
B) kidney.
C) heart.
D) liver.

Question 6

The most effective component to treat a patient with von Willebrand's disease is:

A) fresh frozen plasma.
B) red blood cells.
C) platelets.
D) cryoprecipitated AHF.

Question 7

Which of the following contributes to red cell loss in chronic renal disease?

A) Below normal erythropoietin levels
B) Shearing of red cells from kidney dialysis
C) Elevated uremia
D) All of the above

Question 8

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Reduce the risk of allergic reactions

Question 9

A patient demonstrated the following symptoms: hypotension, tachycardia, cold or clammy skin, and cyanosis. What is the most likely cause?

A) Anaphylactic shock
B) Graft-versus-host disease
C) Congestive heart failure
D) Hypovolemic shock

Question 10

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Treatment of symptomatic anemia

Question 11

Massive transfusion is defined as the replacement of 1 blood volume. In a 70-kg adult, this is equivalent to __________ units of whole blood.

A) 6
B) 8
C) 10
D) 12

Question 12

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Bleeding due to thrombocytopenia

Question 13

Infants do not require crossmatching if they are less than:

A) 6 months old.
B) 5 months old.
C) 4 months old.
D) Crossmatching is always required.

Question 14

Which of the following is used in the treatment of hemophilia B?

A) Factor VIII concentrate
B) Factor XIII concentrate
C) Platelets
D) Fresh frozen plasma

Question 15

The goal of therapeutic apheresis may be to:

A) reduce a high antibody level.
B) replace cellular elements.
C) clear immune complexes.
D) all of the above.

Question 16

Common complications of chemotherapy include:

A) bleeding.
B) infection.
C) anemia.
D) all of the above.

Question 17

Why do premature neonates require red blood cell transfusions?

A) Iatrogenic blood loss
B) Hemoglobin F is being changed to hemoglobin A
C) Insufficient erythropoiesis
D) All of the above

Question 18

Cytomegalovirus-negative blood is required for which category of patients?

A) Sickle cell
B) Neonatal
C) Cardiac
D) Trauma

Question 19

Risk factors for bleeding during cardiac surgery include all of the following except:

A) length of time on the pump.
B) level of preoperative medications.
C) presence of a red cell antibody.
D) hypothermia.

Question 20

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Intravascular volume expansion

Question 21

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Thrombotic thrombocytopenic purpura

Question 22

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Deficiency of factors II, V, X, and XI

Question 23

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Specific clotting deficiencies of VIII, V, and X

Question 24

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Deficiency of factor XIII and von Willebrand's factor

Question 25

Match the component with the indications for use. Each can be used more than once.
a.Cryoprecipitated AHF
b.Fresh frozen plasma
c.Red blood cells
d.Platelets
e.Leukoreduced blood components
f.Washed red blood cells
g.Albumin/plasma protein fraction
h.Factor concentrates
i.Plasma, cryoprecipitate reduced
j.Irradiated blood products
Avoid graft-versus-host disease