Deck 17: Therapeutic Agents for the Musculoskeletal System

Question 1

Skeletal muscle relaxants require which one of the following auxiliary labels?

A)Take with a full glass of water.
B)Take on an empty stomach.
C)Avoid grapefruit juice.
D)May cause dizziness or drowsiness.Avoid alcohol.

Answer 1

D
Skeletal muscle relaxants may cause dizziness and drowsiness, and alcohol can intensify these effects.

Question 2

Which of the following osteoporosis agents can be intravenously (IV) administered?

A)Actonel
B)Boniva
C)Fosamax
D)A and B

Answer 2

B
Boniva may be administered 3 mg IV bolus every 3 months, as well as orally. Actonel and Fosamax are only available orally.

Question 3

All of the following statements are true about gout except:

A)Gout is a form of arthritis.
B)It can be exacerbated by the intake of alcohol.
C)Gout is not related to diet.
D)It can be treated with colchicine.

Answer 3

C
Gout is a form of arthritis that occurs when uric acid builds up in the blood, leading to the development of uric acid crystals in the joint and resulting in inflammation and pain. A variety of nonpharmacologic interventions can be made to decrease the risk of gout attacks. Weight loss, abstaining from alcohol, and adopting a low purine diet (i.e., avoiding meats such as beef, lamb, and pork) can be particularly beneficial. Therapies include colchicine, NSAIDs, and corticosteroids, as well as maintaining low uric acid levels by using uricosuric drugs or xanthine oxidase inhibitors.

Question 4

What organ is affected by an overdose of acetaminophen?

A)Kidney
B)Liver
C)Heart
D)Bladder

Question 5

Generic ibuprofen is marketed as:

A)Advil
B)Naprosyn
C)Motrin
D)A and C

Question 6

Which of the following is not a function of the skeletal system?

A)Structural support and protection
B)Facilitates movement
C)Storage site for sodium and potassium
D)Storage bank for calcium and phosphorus

Question 7

Osteoporosis:

A)Is a systemic skeletal disease.
B)Occurs when bone breaks down faster than it can be rebuilt.
C)Leads to fragile bones.
D)All of the above are accurate descriptions of osteoporosis.

Question 8

All of the following osteoporosis agents are in the same class except:

A)Fosamax
B)Boniva
C)Actonel
D)Evista

Question 9

Opioid analgesics:

A)Treat the cause of the pain.
B)Are scheduled and potentially addictive medications.
C)Block the perception of pain in the CNS.
D)Both B and C accurately describe opioid analgesics.

Question 10

Opioid analgesics require the following auxiliary label(s):

A)May cause dizziness or drowsiness.
B)Avoid alcohol.
C)"Caution: Federal law prohibits the transfer of this drug to any person other than the patient for whom it was prescribed."
D)All of the above auxiliary labels are required for opioid analgesic medications.

Question 11

What is the most severe side effect of opioid medications?

A)Gastrointestinal (GI) upset
B)Respiratory depression
C)Drowsiness
D)Constipation

Question 12

The only COX-2 inhibitor available in the United States is:

A)Celebrex
B)Vioxx
C)Mobic
D)Motrin

Question 13

A negative GI side effect associated with first-generation nonsteroidal antiinflammatory drugs (NSAIDs) is due to:

A)Inhibiting cyclooxygenase-1 (COX-1) enzymes
B)Inhibiting cyclooxygenase-2 (COX-2) enzymes
C)Inhibiting COX-1 and COX-2 enzymes
D)Stimulating COX-1 and COX-2 enzymes

Question 14

All of the following medications have antipyretic, antiinflammatory, and analgesic effects except:

A)Aspirin
B)Acetaminophen
C)Ibuprofen
D)Naproxen

Question 15

Both depolarizing and nondepolarizing neuromuscular-blocking agents affect the neurotransmitter ______________.

A)Epinephrine
B)Norepinephrine
C)Dopamine
D)Acetylcholine

Question 16

Which one of the following drugs is a schedule III controlled substance (C-III) medication?

A)Tylenol with codeine
B)Ultram
C)Percocet
D)Duragesic

Question 17

Why would acetaminophen be chosen over aspirin for a patient taking warfarin?

A)Acetaminophen is a more effective antiinflammatory agent.
B)Acetaminophen does not inhibit platelet action.
C)Acetaminophen is a risk-free medication.
D)None of the above statements apply.

Question 18

Reye syndrome has been linked to what medication?

A)Acetaminophen
B)Diphenhydramine
C)Acetylsalicylic acid
D)None of the above

Question 19

Which of the following risk factors contribute(s) to the development of osteoarthritis?

A)Advanced age
B)Obesity
C)Overuse and trauma of the joints
D)All of the above

Question 20

Baclofen (Lioresal) belongs to what classification of medication?

A)Skeletal muscle relaxants
B)NSAIDs
C)Osteoporosis agents
D)Analgesics

Question 21

Which medication(s) inhibit(s) COX-1 and COX-2 enzymes?

A)Celebrex
B)Tylenol
C)Vicodin
D)B and C

Question 22

Osteoarthritis is considered to be a(an):

A)Autoimmune disease
B)Degenerative joint disease
C)Musculoskeletal disease
D)A and B

Question 23

Which medication do many people take for the prophylaxis (prevention) of heart attacks and strokes?

A)Aspirin
B)Acetaminophen
C)Ibuprofen
D)Calcium

Question 24

Fosamax, Actonel, and Evista are all used for:

A)Osteoporosis
B)Osteoarthritis
C)Gout
D)Skeletal muscle pain

Question 25

The maximum recommended daily dose of acetaminophen for healthy adults is _________ milligrams.

A)1000
B)2000
C)3000
D)4000

Question 26

The role of the skeletal system is to:

A)Provide support for the body.
B)Protect internal organs.
C)Facilitate movement.
D)All of the above are roles of the skeletal system.

Question 27

Which OTC supplements can be taken to help prevent osteoporosis?

A)Vitamin D and calcium
B)Vitamin E and calcium
C)Evista and calcium
D)Iron and calcium

Question 28

Why does acetaminophen not have an antiinflammatory effect?

A)Acetaminophen does not inhibit cyclooxygenase.
B)It only inhibits COX-2 enzymes.
C)Acetaminophen only inhibits cyclooxygenase within the CNS.
D)None of the above answers apply.

Question 29

Which medication can be used to reverse the effects of opioid analgesics?

A)hydromorphone (Dilaudid)
B)meperidine (Demerol)
C)naloxone (Narcan)
D)Codeine

Question 30

Bones serve as storage areas for which mineral(s)?

A)Calcium
B)Sodium
C)Phosphorus
D)A and C

Question 31

Which of the following medications is a combination product that includes acetaminophen?

A)Ultram
B)Percocet
C)Robaxin
D)Dilaudid

Question 32

An antipyretic medication is used to:

A)Reduce pain
B)Reduce fever
C)Prevent gout
D)Treat gout