Deck 27: Treatment of Irritable Bowel Syndrome, ulcerative Colitis, and Crohns Disease

Question 1

Which of the following warning labels should be placed on a prescription for Lomotil?

A)May not refill.
B)May cause nausea.
C)May be habit forming.
D)May cause dark urine.

Answer 1

May be habit forming.

Question 2

Which drug is a serotonin receptor antagonist used to control diarrhea caused by severe IBS?

A)Infliximab
B)Lomotil
C)Alosetron
D)Tegaserod

Answer 2

Alosetron

Question 3

One of the only FDA-approved anticholinergic drugs used in the treatment of IBS when diarrhea is the primary symptom is _____.

A)atropine
B)difenoxin + atropine
C)loperamide
D)doxycycline

Answer 3

atropine

Question 4

Aminosalicylates work via what mechanism?

A)They stimulate the evacuation of the bowel.
B)Bacteria in the colon metabolize the drug and release 5-ASA,reducing inflammation in the bowel.
C)They stimulate the production of 5-HT in the intestines,which inhibits inflammation in the bowel.
D)They produce amino acids in the bowel to help with digestion and evacuation of the bowel.

Question 5

Which of the following would most likely be used to relieve constipation for IBS?

A)Lomotil
B)Atropine
C)Polycarbophil
D)Alosetron

Question 6

The main difference between ulcerative colitis and Crohn's disease is ulcerative colitis causes inflammation _____.

A)in the upper lining of the small intestine and colon,whereas Crohn's disease causes inflammation deep in the lining of the colon wall
B)throughout the GI tract,and Crohn's disease causes inflammation only in the colon
C)deep in the lining of the colon,whereas Crohn's disease causes inflammation in the upper lining of the colon wall
D)only in the colon,and Crohn's disease causes inflammation throughout the GI tract

Question 7

Which of the following diseases is treated by administering prostaglandin E₁ derivatives?

A)Ulcerative colitis
B)IBS
C)Crohn's disease
D)All of the above

Question 8

Which of the following foods may aggravate IBS?

A)Cheese
B)Strawberries
C)Fiber bars
D)Tomatoes

Question 9

Which of the following anticholinergics is used to treat IBS?

A)Dyclonine
B)Diphenhydramine
C)Dicyclomine
D)Doxycycline

Question 10

IBS tends to affect _____ predominately.

A)men
B)children
C)women
D)elderly

Question 11

Which of the following may occur when taking an anticholinergic for IBS?

A)Urinary incontinence
B)Mydriasis
C)Vomiting
D)Excessive salivation

Question 12

Which of the following is a possible cause for IBS?

A)Stressful work environment
B)Seasonal allergies
C)Occasional alcohol
D)Oversensitive stomach

Question 13

Which of the following explains how serotonin can affect IBS?

A)Decreased levels of 5-HT in the gastrointestinal (GI)tract increase motility.
B)Decreased levels of 5-HT in the GI tract can increase its pain sensitivity.
C)Increased levels of 5-HT in the GI tract increase its pain sensitivity.
D)Increased levels of 5-HT in the GI tract can decrease motility.

Question 14

Which of the following warning labels might be placed on a prescription for prostaglandin E₁ derivatives?

A)May cause dizziness.
B)May cause nausea.
C)Take on an empty stomach.
D)May cause drowsiness.

Question 15

Irritable bowel syndrome (IBS)is sometimes referred to as _____.

A)peristalsis
B)ulcerative colitis
C)peptic ulcer disease
D)colitis

Question 16

_____ can be prescribed when constipation is the predominate symptom of IBS in women.

A)Diphenhydramine
B)Loperamide
C)Lubiprostone
D)Dicyclomine

Question 17

Which of the following is not an opioid antidiarrheal?

A)Difenoxin
B)Diphenoxylate
C)Loperamide
D)Dicyclomine

Question 18

Explain what you may say to a patient who is requesting a refill for alosetron.

A)"I will have to contact your doctor to authorize a refill for you."
B)"Refills are not allowed for this prescription."
C)"I will process your request right away."
D)"You must see your physician to request a refill."

Question 19

How do bulk-forming laxatives work to relieve constipation?

A)They absorb liquid in the colon to help form a bulky stool and stimulate evacuation.
B)They absorb liquid in the small intestine to help form a bulky stool and stimulate evacuation.
C)They inhibit existing bacteria in the bowel from growing,promoting fluid absorption and easier evacuation.
D)They inhibit the absorption of fluid in the intestines to allow for stimulation of a bowel movement.

Question 20

In which case would Motofen not be recommended for treatment?

A)IBS
B)Ulcerative colitis
C)Crohn's disease
D)IBD

Question 21

Which of the following is a systemic adverse reaction to corticosteroid treatment of ulcerative colitis?

A)Mood swings
B)Drowsiness
C)Local itching
D)Appetite change

Question 22

MATCHING
Match each of the following generic names with its corresponding trade name.
a.Imodium
b.Remicade
c.Asacol
d.Bentyl
e.Fibercon
Mesalamine

Question 23

Why would reducing budesonide help treat Crohn's disease?

A)Reducing prostaglandins allows the bowel to absorb fluids,making evacuation easier.
B)Reducing prostaglandins helps increase the inflammation and immune response.
C)Decreasing prostaglandin synthesis helps reduce inflammation.
D)Decreasing prostaglandin synthesis allows the disease to go into remission.

Question 24

Which of the following is commonly prescribed for treatment of infected fistulas that may have developed as a result of Crohn's disease?

A)Doxycycline
B)Amitriptyline
C)Fluconazole
D)Metronidazole

Question 25

How would an antibiotic and sulfasalazine interact when taken together?

A)Bacteria that would normally metabolize sulfasalazine would be eradicated by the antibiotic.
B)Antibiotics tend to cause diarrhea,reducing the absorption of sulfasalazine.
C)Antibiotics and sulfasalazine are metabolized by the same mechanism in the body,reducing their elimination from the body.
D)Sulfasalazine would help increase the production of the unwanted bacteria in the body,causing the need for an increased dose of antibiotics.

Question 26

Antimetabolites are used in the treatment of Crohn's disease to ______.

A)reduce inflammation
B)control diarrhea
C)induce remission
D)enhance the immune system

Question 27

What is the benefit of taking the prodrug sulfasalazine?

A)Prodrugs tend to have fewer adverse effects.
B)Prodrugs are less harsh on the GI tract.
C)Prodrugs are the active metabolite in pill form increasing distribution of the drug.
D)Prodrugs have improved bioavailability when taken orally.

Question 28

Which of the following is an aminosalicylate used in the treatment of IBD?

A)Olanzapine
B)Mecamylamine
C)Mesalamine
D)Molsidomine

Question 29

To help reduce inflammation when treating ulcerative colitis,_____ can be taken.

A)balsalazide
B)olanzapine
C)dicyclomine
D)budesonide

Question 30

MATCHING
Match each of the following generic names with its corresponding trade name.
a.Imodium
b.Remicade
c.Asacol
d.Bentyl
e.Fibercon
Dicyclomine

Question 31

Which of the following populations should not take Remicade?

A)Teenage females
B)Adult females
C)Teenage males
D)Adult males

Question 32

Which of the following is an immunomodulator used to treat Crohn's disease?

A)Omalizumab
B)Rituximab
C)Alemtuzumab
D)Infliximab

Question 33

MATCHING
Match each of the following generic names with its corresponding trade name.
a.Imodium
b.Remicade
c.Asacol
d.Bentyl
e.Fibercon
Loperamide

Question 34

MATCHING
Match each of the following generic names with its corresponding trade name.
a.Imodium
b.Remicade
c.Asacol
d.Bentyl
e.Fibercon
Infliximab

Question 35

MATCHING
Match each of the following generic names with its corresponding trade name.
a.Imodium
b.Remicade
c.Asacol
d.Bentyl
e.Fibercon
Polycarbophil

Question 36

Which of the following drugs would be used to help reduce inflammation of Crohn's disease?

A)Hydrocortisone suppository
B)Hydrocodone tablets
C)Prednisone tablets
D)Hydrocortisone suppository.