Deck 37: Treatment of Cancers

Question 1

Which of the following is given intramuscularly after antiestrogen therapy for estrogen receptor (ER)-positive metastatic breast cancer in postmenopausal women with disease progression?

A)Fulvestrant
B)Exemestane
C)Goserelin
D)Megestrol acetate

Answer 1

Fulvestrant

Question 2

_____ is used to treat inoperable,metastatic endometrial cancer and renal cell cancer.

A)Megestrol
B)Medroxyprogesterone acetate
C)Mitomycin
D)Myleran

Answer 2

Medroxyprogesterone acetate

Question 3

_____ is associated with causing cancer of the cervix.

A)EBV
B)HPV
C)HIV
D)HBV

Answer 3

HPV

Question 4

Which of the following is used as a first-line of treatment for postmenopausal women with advanced or metastatic ER-positive breast cancer?

A)Tamoxifen
B)Megestrol
C)Cyclophosphamide
D)Anastrozole

Question 5

Two screening tests used for the diagnosis of colorectal cancer are colonoscopy and _____.

A)proctoscopy
B)fecal occult blood test (FOBT)
C)enteroscopy
D)stool color test

Question 6

_____ is associated with causing stomach cancer.

A)H.pylori
B)Staphylococcus
C)E.coli
D)C.difficile

Question 7

_____ can be used to treat metastatic breast cancer in postmenopausal women.

A)Bleomycin
B)Toremifene
C)Carboplatin
D)Cisplatin

Question 8

A _____ tumor is cancerous and can invade and destroy nearby tissue and metastasize to other parts of the body.

A)benign
B)malignant
C)neoplasia
D)protoplasmic

Question 9

_____ is a method used to describe how far the cancer has progressed within in the body.

A)Staging
B)Priming
C)Deoxyribonucleic acid (DNA)testing
D)Biopsy

Question 10

Endometrial cancer most commonly affects _____.

A)postmenopausal women
B)perimenopausal women
C)young adults
D)middle-aged men

Question 11

The most common form of cancer is _____ cancer.

A)breast
B)prostate
C)lung
D)cervical

Question 12

The most treatable form of skin cancer is _____.

A)melanoma
B)dermatome
C)Kaposi's sarcoma
D)nonmelanoma

Question 13

Lymphoma's primary site of growth begins in the _____.

A)cells of the immune system
B)blood-forming tissues
C)tissues covering the internal organs
D)white blood cells

Question 14

The use of drugs to kill or slow the growth of cancerous cells is called _____.

A)biological therapy
B)pharmaceutical therapy
C)chemotherapy
D)modulator therapy

Question 15

Examples of ionizing radiation include all of the following except _____.

A)x-rays
B)ultraviolet (UV)light
C)radon gas
D)PCBs

Question 16

Cancer-causing chemicals called _____ are found in the workplace,home,and the environment through pollution.

A)teratogens
B)mutagens
C)carcinogens
D)hemogens

Question 17

All chemotherapy agents are prepared in a _____ biohazard safety cabinet containing a high-efficiency particulate air (HEPA)filter with a _____ flow of air.

A)Class III,horizontal
B)Class I,vertical
C)Class I,horizontal
D)Class II,vertical

Question 18

A diet that is high in _____ may increase the risk of cancers of the colon,uterus,and prostate.

A)carbohydrates
B)protein
C)sugars
D)fats

Question 19

The oldest class of antineoplastic agents is _____.

A)phosphamides
B)alkerans
C)alkylating agents
D)phosphorylating agents

Question 20

Why are alkylating agents toxic to cancer cells and noncancer cells?

A)They destroy all pathways of ribonucleic acid (RNA),including noncancerous cells.
B)They damage necessary enzymes to cease DNA synthesis in all cells.
C)They damage DNA and impair DNA replication.
D)Alkylating agents are one of the few classes that are toxic only to cancer cells.

Question 21

_____ is a platinum compound that used for the treatment of testicular and ovarian cancer.

A)Cisplatin
B)Carboplatin
C)Oxaliplatin
D)Capecitabine

Question 22

Methotrexate (MTX)is the principal drug in the _____ class.

A)fluoropyrimidine
B)platinum compound
C)antimetabolite
D)topoisomerase inhibitor

Question 23

Paclitaxel and docetaxel are cytotoxic drugs that are naturally derived from the _____ yew and _____ yew trees.

A)Western,European
B)Pacific,European
C)European,American
D)Western,American

Question 24

How does MTX cause cells to die?

A)MTX depletes the necessary amino acids to cease DNA synthesis.
B)It forms abnormal nucleic acid pairs by inhibiting the formation of cancerous cell walls.
C)It inhibits DNA synthesis by diminishing essential DNA nucleosides.
D)It causes cell mutations,inhibiting further replication.

Question 25

_____ is a miscellaneous cancer drug agent that is approved for the treatment of head and neck cancer.

A)Porfimer
B)Dactinomycin
C)Mitomycin
D)Bleomycin

Question 26

Which of the following anthracyclines is a prodrug with a long half-life allowing it be administered weekly or monthly?

A)Idarubicin
B)Epirubicin
C)Doxorubicin
D)Mitoxantrone

Question 27

Vinorelbine,vincristine,and vinblastine are naturally derived from the_____ plant.

A)foxglove
B)aloe
C)periwinkle
D)rosehips

Question 28

Etoposide and teniposide are semisynthetic derivatives of an extract from the _____ plant.

A)mandarin
B)mandrake
C)cinchona
D)marigold