Deck 38: Vaccines, Immunomodulators, and Immunosuppressants

Question 1

Which of the following classifications of drugs are not categorized as immunopharmacologicals?

A)Corticosteroids
B)Antineoplastics
C)Antivirals
D)Cytokine inhibitors

Answer 1

Antivirals

Question 2

An example of a conjugate vaccine is _____.

A)Haemophilus influenzae type B (Hib)
B)flu
C)mumps
D)varicella

Answer 2

Haemophilus influenzae type B (Hib)

Question 3

What must be done when a breach in the "cold chain" occurs for vaccines?

A)Freeze the product.
B)Refrigerate the product within 24 hours.
C)Bring the product to the correct temperature quickly.
D)Destroy the product.

Answer 3

Destroy the product.

Question 4

Which of the following macrolide immunosuppressants is indicated to prevent transplant rejections?

A)Everolimus
B)Temsirolimus
C)Belatacept
D)Pimecrolimus

Question 5

MATCHING
Match the following trade and generic drug names.
a.Mycophenolate mofetil
b.Pimecrolimus
c.Tacrolimus
d.Daclizumab
e.Cyclosporine
Prograf

Question 6

Mycophenolic acid is an immunosuppressive agent that inhibits the enzyme required for synthesis of purines needed for _____.

A)T-cell lymphocytes
B)T-cell and B-cell proliferation
C)B-cell antibodies
D)inhibition of CYP450 microsomal pathways

Question 7

The flu vaccine must be reformulated every _____.

A)6 months
B)year
C)24 months
D)5 years

Question 8

Immunosuppressants are used for all of the following disease states except _____.

A)multiple sclerosis (MS)
B)muscular dystrophy (MD)
C)rheumatoid arthritis (RA)
D)systemic lupus erythematosus (SLE)

Question 9

Which of the following entities must keep the cold chain for vaccines and immunologicals unbroken?

A)Manufacturer
B)Pharmacy
C)Physician's office
D)All of the above

Question 10

Antithymocyte globulin (ATG)is administered primarily to _____.

A)reduce rejection associated with organ and bone marrow transplantation.
B)boost the immune system of the immunosuppressed patient
C)provide protection against infections attacking the immunosuppressed patient
D)treat eczema

Question 11

A person taking belatacept should not receive which of the following vaccines?

A)Hepatitis A
B)Tetanus
C)Rubella
D)Meningococcal

Question 12

Which of the following is not an example of a live vaccine?

A)Polio
B)Mumps
C)Tetanus
D)Rubella

Question 13

The immunomodulator basiliximab is used to _____.

A)treat advanced renal cancer
B)block transcription of cytokines and interleukins
C)encourage T-cell proliferation
D)prolong the life of transplanted organs

Question 14

Why is RhoGAM administered to pregnant women with Rh negative blood?

A)To prevent pregnant women from making Rh positive antibodies
B)To inhibit the transmission of Rh negative antibodies to an Rh positive child
C)To prevent the production of Rh negative antibodies
D)To limit the exposure of Rh positive antibodies to a Rh positive child

Question 15

The temperature that must be maintained for an uninterrupted cold chain from the manufacturer to its final destination is _____.

A)2° to 6° F
B)2° to 8° C
C)32° to 59° C
D)59° to 86° F

Question 16

Which of the following would be the least affected by a breach in the "cold chain"?

A)Biological solutions
B)Vaccines
C)Dry powders
D)Biological suspensions

Question 17

Why does the body reject transplanted organs and not manufactured parts?

A)Manufactured parts are made specifically for an individual so that they won't be rejected.
B)Most manufactured parts are made from products that would not create antigens to cause a rejection.
C)Manufactured parts do not have any blood flow to them so there is less chance of them causing rejection.
D)The body rejects manufactured parts just as equally as it rejects transplanted organs.

Question 18

Which of the following drugs works by suppressing cell destruction in graft-versus-host reactions?

A)Tacrolimus
B)Cyclosporine
C)Atgam
D)CellCept

Question 19

Tetanus and diphtheria are examples of _____ vaccines.

A)conjugated
B)live,attenuated
C)toxoid
D)inactivated,killed

Question 20

Sirolimus interferes with a key enzyme that regulates the second phase of T-cell activation and proliferation and decreases levels of all of the following immunoglobulins except _____.

A)IgM
B)IgG
C)IgD
D)IgA

Question 21

MATCHING
Match the following trade and generic drug names.
a.Mycophenolate mofetil
b.Pimecrolimus
c.Tacrolimus
d.Daclizumab
e.Cyclosporine
Zenapax

Question 22

MATCHING
Match the following trade and generic drug names.
a.Mycophenolate mofetil
b.Pimecrolimus
c.Tacrolimus
d.Daclizumab
e.Cyclosporine
CellCept

Question 23

MATCHING
Match the following trade and generic drug names.
a.Mycophenolate mofetil
b.Pimecrolimus
c.Tacrolimus
d.Daclizumab
e.Cyclosporine
Elidel

Question 24

MATCHING
Match the following trade and generic drug names.
a.Mycophenolate mofetil
b.Pimecrolimus
c.Tacrolimus
d.Daclizumab
e.Cyclosporine
Sandimmune