Deck 16: Treatment of Osteoporosis and Pagets Disease of the Bone

Question 1

Why would the inhibition of osteoclast activity be beneficial in the treatment of osteoporosis?

A)It increases calcium in the blood to help promote bone formation.
B)It inhibits osteolysis.
C)It allows for an increased production of bone-forming enzymes.
D)It stimulates osteolysis because osteoclast activity is inhibited.

Answer 1

It inhibits osteolysis.

Question 2

Which of the following should have a "Take on an empty stomach" warning label?

A)Ibandronate
B)Raloxifene
C)Teriparatide
D)Estradiol

Answer 2

Ibandronate

Question 3

Which of the following is not a pharmacological treatment goal for osteoporosis?

A)Increase bone density.
B)Prevent all fractures from happening.
C)Reduce risks for future fractures.
D)Decrease the formation of bone.

Answer 3

Decrease the formation of bone.

Question 4

Which of the following must be administered by intravenous (IV)infusion?

A)Etidronate
B)Tiludronate
C)Risedronate
D)Pamidronate

Question 5

Vitamin _____ is involved in the formation of osteoclasts.

A)A
B)B
C)C
D)D

Question 6

Which of the following foods has the least amount of calcium in it?

A)Cottage cheese
B)Soy beans
C)Broccoli
D)Low-fat plain yogurt

Question 7

Which of the following is not responsible for the regulation of serum calcium levels?

A)Parathyroid hormone (PTH)
B)Calcitonin
C)Vitamin A
D)Vitamin D

Question 8

Paget's disease is most common in which sex and age group?

A)Women older than 55 years
B)Men older than 55 years
C)Women older than 70 years
D)Men older than 70 years

Question 9

Calcium carbonate should be taken _____.

A)first thing in the morning
B)just before bedtime
C)on an empty stomach
D)after eating a meal

Question 10

Which of the following is only administered once a year?

A)Alendronate
B)Zoledronic acid
C)Ibandronate
D)Risedronate

Question 11

Calcium _____ is most absorbable and easiest to tolerate.

A)carbonate
B)citrate
C)gluconate
D)chloride

Question 12

Of the following,which drug is the least potent bisphosphonate?

A)Etidronate
B)Alendronate
C)Risedronate
D)Pamidronate

Question 13

What can be the extent of damage of Paget's disease on the body?

A)Affects the limbs only
B)Entire skeleton may be affected
C)Affects only joints
D)Affects only the hips

Question 14

Fractures caused by osteoporosis when coughing or sneezing are classified as _____ fractures.

A)low-impact
B)bone density
C)spinal
D)fragility

Question 15

Of the following substances of abuse,which one can produce osteoporosis?

A)Cocaine
B)Alcohol
C)Hydrocodone
D)Marijuana

Question 16

A chronic,progressive disease of bone characterized by loss of bone density and bone strength and resulting in increased fracture risk is called _____.

A)rheumatoid arthritis (RA)
B)osteoporosis
C)brittle bone disease
D)osteosarcoma

Question 17

The precursor to osteoporosis is ______.

A)osteopenia
B)osteoblastosis
C)osteosarcoma
D)osteoma

Question 18

Which of the following drugs is an anabolic treatment for osteoporosis?

A)Raloxifene
B)Risedronate
C)Teriparatide
D)Calcitonin

Question 19

Why would hyperparathyroidism cause osteoporosis?

A)Promotes calcium to be released from bones,causing an increased level of calcium in blood
B)Blocks the pathway in which calcium is absorbed through the gastrointestinal (GI)tract
C)Hinders the release of estrogen,which inhibits bone formation
D)Decreases the ability of calcium to be reabsorbed into the bone

Question 20

Raloxifene is indicated for the treatment and prevention of osteoporosis in _____ women.

A)perimenopausal
B)menopausal
C)postmenopausal
D)geriatric

Question 21

MATCHING
Match the following trade and generic drug names.
a.Raloxifene
b.Etidronate
c.Alendronate
d.Zoledronic acid
e.Pamidronate
Aredia

Question 22

Which of the following is a genetically engineered form of human PTH and carries a serious risk for developing osteosarcoma?

A)Raloxifene
B)Risedronate
C)Teriparatide
D)Calcitonin

Question 23

MATCHING
Match the following trade and generic drug names.
a.Raloxifene
b.Etidronate
c.Alendronate
d.Zoledronic acid
e.Pamidronate
Evista

Question 24

Which of the following is not a way PTH analogues work to treat osteoporosis?

A)Increase the rate of bone remodeling.
B)Thicken structural units of bone (osteons).
C)Produce bone architecture that closely resembles normal bone.
D)Inhibit bone resorption.

Question 25

MATCHING
Match the following trade and generic drug names.
a.Raloxifene
b.Etidronate
c.Alendronate
d.Zoledronic acid
e.Pamidronate
Fosamax

Question 26

MATCHING
Match the following trade and generic drug names.
a.Raloxifene
b.Etidronate
c.Alendronate
d.Zoledronic acid
e.Pamidronate
Didronel

Question 27

Which of the following can be administered intranasally?

A)Calcitonin
B)Raloxifene
C)Estropipate
D)Pamidronate

Question 28

MATCHING
Match the following trade and generic drug names.
a.Raloxifene
b.Etidronate
c.Alendronate
d.Zoledronic acid
e.Pamidronate
Reclast