Deck 3: Pharmacodynamics

Question 1

Patient- related factors such as the presence of _____ increase or decrease a person's response to an administered drug.

A)chronic disease
B)drug allergies
C)obesity
D)all of the above

Answer 1

D
Patient-related factors,such as the presence of chronic disease,drug allergies,age,obesity,or gender,increase or decrease a person's response to an administered drug.

Question 2

_____ is ratio of the effective dose to the lethal dose.

A)Dose-response curve
B)Therapeutic index
C)Maximum dose curve
D)Margin

Answer 2

B
Therapeutic index (TI)is ratio of the effective dose to the lethal dose.

Question 3

MATCHING
Match the following terms and causes.
A.adverse reactions
b.hepatotoxicity
c.nephrotoxicity
d.teratogens
e.carcinogen
can be caused by ibuprofen

Answer 3

C

Question 4

In a _____,some of the people in the study will receive a drug containing active ingredient and others will receive a drug look-alike that does not contain active ingredients.

A)blind study
B)single-blind study
C)double-blind study
D)open study

Question 5

MATCHING
Match the following terms and causes.
A.adverse reactions
b.hepatotoxicity
c.nephrotoxicity
d.teratogens
e.carcinogen
brings harm to developing fetus

Question 6

A(n)_____ is a drug that binds to and activates the receptor site eliciting a cellular response.

A)antagonist
B)agonist
C)partial antagonist
D)partial agonist

Question 7

_____ is an example of a pure antagonist.

A)Naproxen
B)Niacin
C)Naloxone
D)Nifedipine

Question 8

MATCHING
Match the following terms and causes.
A.adverse reactions
b.hepatotoxicity
c.nephrotoxicity
d.teratogens
e.carcinogen
stimulate growth of cancer

Question 9

The dose-response curve shows the drug's relative _____ and _____.

A)efficacy and strength
B)efficacy and potency
C)potency and mechanism of action
D)sensitivity and efficacy

Question 10

Unexpected drug reactions are known as _____ reactions.

A)idiosyncratic
B)adverse
C)pharmacodynamic
D)dose-response

Question 11

Repeated exposures to a drug,particularly narcotics,may result in a(n)_____ response to the drug.

A)increased
B)normal
C)decreased
D)adverse

Question 12

MATCHING
Match the following terms and causes.
A.adverse reactions
b.hepatotoxicity
c.nephrotoxicity
d.teratogens
e.carcinogen
undesired effects

Question 13

_____,a drug used to treat heart disease,has a narrow therapeutic index.

A)Aspirin
B)Warfarin
C)Heparin
D)Digoxin

Question 14

Drug doses for children are often calculated according to the child's _____ and _____.

A)weight and body surface area
B)body surface area and height
C)height and weight
D)a and b

Question 15

MATCHING
Match the following terms and causes.
A.adverse reactions
b.hepatotoxicity
c.nephrotoxicity
d.teratogens
e.carcinogen
can be caused by acetaminophen