Question 1

Imatinib (Gleevec)is indicated as treatment for which of the following types of cancer?&#10;A)Chronic myeloid leukemia&#10;B)Acute lymphocytic leukemia&#10;C)Chronic lymphocytic leukemia&#10;D)Acute myeloid leukemia

Accepted Answer

Imatinib is indicated for the treatment of chronic myeloid leukemia (CML),particularly after failure of interferon alfa therapy.Imatinib is one of the newest available antineoplastic drugs.

Question 2

A patient is receiving alkylating drugs.The nurse knows that which of the following signs may indicate an oncological emergency?&#10;A)Cracked lips&#10;B)Temperature of 37.8&#176;C&#10;C)Diarrhea&#10;D)Dry cough

Accepted Answer

Fever and chills with a temperature of 37.8°C or higher indicate an oncological emergency,and the physician should be contacted immediately.
The physician should also be contacted immediately in the case of sores or cracks in the mouth,diarrhea that lasts more than 2 or 3 days,and a persistent cough.

Question 3

Patients receiving antineoplastic drugs should be advised to take which of the following medications for minor aches and pains?&#10;A)ibuprofen (Motrin)&#10;B)acetylsalicylic acid (Aspirin)&#10;C)acetaminophen (Tylenol)&#10;D)naproxen

Accepted Answer

Acetaminophen has no effect on bleeding.
Patients receiving chemotherapy drugs should avoid nonsteroidal anti-inflammatory drugs (NSAIDS),such as ibuprofen,acetylsalicylic acid,and naproxen,due to the increased risk of bleeding.

Question 4

Large,cumulative doses of doxorubicin (Adriamycin),a cytotoxic antibiotic,are known to cause which of the following adverse effects?&#10;A)Severe emesis&#10;B)Cardiomyopathy&#10;C)Lung disease&#10;D)Nephrotoxicity

Accepted Answer

Severe cases of cardiomyopathy are associated with large,cumulative doses of doxorubicin.Routine monitoring of cardiac ejection fraction is needed.

Question 5

A patient is receiving cisplatin as part of her treatment for ovarian cancer.Which nursing diagnosis is appropriate for this antineoplastic drug?&#10;A)Ineffective tissue perfusion related to cardiotoxicity&#10;B)Disturbed sensory perception related to ototoxicity&#10;C)Activity intolerance related to anemia-induced fatigue&#10;D)Impaired urinary elimination pattern related to hyperuricemia

Accepted Answer

Activity intolerance related to anemia-induced fatigue is an appropriate nursing diagnosis specific to cisplatin.

Question 6

Estrogen antagonists can cause hypercalcemia.Which of the following are symptoms of hypercalcemia?&#10;A)Constipation and urinary changes&#10;B)Confusion and tachycardia&#10;C)Lethargy and diarrhea&#10;D)Weakness and hypoventilation

Accepted Answer

Assessment associated with the use of estrogen antagonists includes monitoring for the adverse effects of hypercalcemia,including constipation,confusion,lethargy,weakness,and changes in urinary patterns.

Question 7

Alkylating drugs can have a profound effect on the patient's nutritional status.Which of the following laboratory results will assist the nurse in determining the impact the drug has had on the patient's nutritional status?

A)White blood cell (WBC)count
B)Platelet count
C)Alanine aminotransferase (ALT) levels
D)Serum albumin levels

Accepted Answer

Serum levels of albumin and protein should be noted,as should fluid and electrolyte levels.

Deck 49: Anti-neoplastic Drugs: Cell Cyclenonspecific and Miscellaneous Drugs