Question 1

Which of the following causes deviations from the law of independent assortment?&#10;A) The genes of interest are on the same chromosome&#10;B) The genes of interest are linked&#10;C) Homologous recombination between genes&#10;D) Nonhomologous recombination&#10;E) Nondisjunction

Accepted Answer

The genes of interest are linked

Question 2

Which of the following is generally true for genetic diseases?&#10;A) The incidence is less than the prevalence&#10;B) The incidence is greater than the prevalence&#10;C) The incidence equals the prevalence

Accepted Answer

Incidence refers to the number of new cases of a disease in a population during a specific time period, while prevalence refers to the total number of cases of a disease in a population at a specific time. Genetic diseases are typically present throughout a person's life, so the number of people affected (prevalence) tends to accumulate over time, resulting in a higher prevalence than the number of new cases (incidence) in a given time period. Therefore, B is the correct answer because the incidence of genetic diseases is usually lower than the prevalence.

Question 3

Which of the following can be used to determine the potential genotypes of offspring from a simple Mendelian cross?&#10;A) Punnett square&#10;B) Hardy-Weinberg equilibrium&#10;C) Bayesian analysis&#10;D) Law of independent assortment&#10;E) Rules of probability

Accepted Answer

Punnett squares are used to determine the potential genotypes of offspring from a simple Mendelian cross. They visually depict the possible combinations of alleles from the parental gametes and predict the ratios of genotypes among the offspring. Hardy-Weinberg equilibrium is used to assess allele and genotype frequencies within populations, not to predict offspring genotypes. Bayesian analysis is a statistical method that can be used in genetic studies, but it is not typically used to predict offspring genotypes. The law of independent assortment and rules of probability are both principles that are applied in Punnett square analyses.

Deck 1: The History and Impact of Genetics in Medicine