Deck 25: Lipid-Lowering Drugs and Atherosclerosis

Question 1

Isolated hypertriglyceridemia is best treated with:

A) Statins
B) Fibric acid derivatives
C) Cholesterol absorption inhibitors
D) Niacin
E) Bile acid sequestrants

Answer 1

Fibric acid derivatives

Question 2

When a patient is intolerant to statin class drugs, the most common second choice for treating LDL cholesterol levels greater than 135 mg/dl is:

A) Bile acid sequestrants
B) Fibric acid derivatives
C) Cholesterol absorption inhibitors
D) Niacin
E) Statins

Answer 2

Fibric acid derivatives

Question 3

Vytorin is a combination of ezetimibe and simvastatin. The pharmacologic effects include:

A) Platelet inhibition
B) Reduction in intestinal absorption of cholesterol
C) Cholesterol-lowering ability independent of plasma lipoprotein levels
D) Inhibition in cholesterol synthesis within hepatocytes
E) A, B, and D

Answer 3

A, B, and D