Deck 9: Inflammation and Immunity

Question 1

Proteins that are increased in the bloodstream during acute inflammation are called

A) membrane attack complexes.
B) selectin receptors.
C) acute phase proteins.
D) major histocompatibility complexes.

Answer 1

acute phase proteins.

Question 2

Interleukin-1,interleukin-6,and tumor necrosis factor-a are inflammatory cytokines secreted by

A) plasma cells.
B) neutrophils.
C) lymphocytes.
D) macrophages.

Answer 2

macrophages.

Question 3

Functions of B cells include

A) synthesizing antibodies.
B) secreting cytokines.
C) killing antigen-presenting cells.
D) stimulating B cells.
E) killing virally infected cells.

Answer 3

synthesizing antibodies.

Question 4

The membrane attack complex formed by complement is similar in function to

A) CD4⁺.
B) granzymes.
C) CD8.
D) perforin.

Question 5

The "classical pathway" for activation of the complement cascade is triggered by

A) activation of C3.
B) inflammation.
C) first recognition of an antigen.
D) antigen-antibody complexes.

Question 6

The primary function of kinins is

A) phagocytosis of antigens.
B) production of antibodies.
C) to limit immune reactions.
D) vasodilation to enhance inflammation.

Question 7

The spleen is an important defense against infection,because it

A) activates the complement cascade.
B) initiates inflammation.
C) controls phagocytosis.
D) filters the blood.

Question 8

Active immunity involves (Select all that apply.)

A) injection of preformed human antibodies.
B) injection of human immune globulin.
C) injection with preformed animal antibodies.
D) vaccines with dead or altered organisms.
E) active infections.

Question 9

Activation of the complement cascade results in (Select all that apply.)

A) antibody production.
B) inflammation.
C) immunosuppression.
D) autoimmunity.
E) chemotaxis.

Question 10

Functions of antibodies include (Select all that apply.)

A) antigen agglutination.
B) antigen precipitation.
C) opsonization.
D) phagocytosis.
E) complement activation.

Question 11

Antigen-presenting cells function to

A) display foreign antigen on their cell surfaces bound to MHC.
B) stimulate cytokine production by macrophages.
C) phagocytose and degrade foreign antigens.
D) initiate the complement cascade by way of the alternative pathway.

Question 12

Leukocytosis with a "shift to the left" refers to

A) elevated segmented neutrophils.
B) elevated immature neutrophils.
C) decreased monocytes.
D) decreased immature neutrophils.

Question 13

Functions of T cells include (Select all that apply.)

A) synthesizing antibodies.
B) secreting cytokines.
C) killing antigen-presenting cells.
D) stimulating of B cells.
E) killing virally infected cells.

Question 14

Passive immunity is provided by (Select all that apply.)

A) transfer of preformed human antibodies.
B) injection of human immune globulin.
C) injection with preformed animal antibodies.
D) vaccines with dead or altered organisms.
E) active infections.

Question 15

The primary function of eosinophils is to

A) kill parasitic helminths (worms).
B) kill bacteria.
C) stop viral replication.
D) phagocytize fungi.

Question 16

The mononuclear phagocyte system consists of (Select all that apply.)

A) monocytes and tissue macrophages.
B) dendritic cells.
C) bone marrow stem cells.
D) antibody-secreting plasma cells.
E) basophils.

Question 17

Characteristics of complement include (Select all that apply.)

A) stimulating chemotaxis.
B) lysing target cells.
C) having multiple plasma proteins.
D) being synthesized in the bone marrow.
E) enhancing phagocytosis.

Question 18

Immunity to a specific organism can be determined by

A) active phase protein count.
B) antibody titer.
C) erythrocyte sedimentation rate.
D) WBC count.

Question 19

Which clinical finding is most indicative of an acute bacterial infection?

A) Increased (band) neutrophils
B) Elevated temperature
C) Elevated erythrocyte sedimentation rate
D) Elevated WBC count