Deck 11: Malignant Disorders of White Blood Cells

Question 1

While in the hospital for management of acute lymphoid leukemia (ALL),a patient develops severe thrombocytopenia.The most appropriate action for this condition is

A) anticoagulant therapy.
B) chemotherapy.
C) activity restriction.
D) isolation.

Answer 1

activity restriction.

Question 2

A 58-year-old woman is seen in the clinic for reports of severe back pain.Her chest x-ray demonstrates generalized bone demineralization and compression fracture.Blood studies demonstrate elevated calcium levels.The most likely diagnosis is

A) leukemia.
B) myeloma.
C) Hodgkin disease.
D) back trauma.

Answer 2

myeloma.

Question 3

Which type of leukemia primarily affects children?

A) ALL (acute lymphoid leukemia)
B) CLL (chronic lymphoid leukemia)
C) AML (acute myeloid leukemia)
D) CML (chronic myeloid leukemia)

Answer 3

ALL (acute lymphoid leukemia)

Question 4

Burkitt lymphoma is most closely associated with

A) Epstein-Barr virus.
B) radiation exposure.
C) immunodeficiency syndromes.
D) history of cigarette smoking.

Question 5

Autologous stem cell transplantation is a procedure in which

A) there is a high rejection rate.
B) stem cells are transferred to the patient from an HLA-matched donor.
C) stem cells are transferred to the patient from an identical twin.
D) stem cells are harvested from the patient and then returned to the same patient.

Question 6

Which group of clinical findings describes the typical presentation of ALL (acute lymphoid leukemia)?

A) Pain in long bones, infection, fever, bruising
B) Vertebral fracture, hypercalcemia, bone pain
C) Elevated WBC count found on routine examination, asymptomatic
D) Painless enlarged cervical lymph node, fever, weight loss

Question 7

Renal insufficiency is a common complication of which disease?

A) Chronic myeloid leukemia (CML)
B) Chronic lymphoid leukemia (CLL)
C) Myeloma
D) Hodgkin disease

Question 8

A patient is diagnosed with stage III non-Hodgkin lymphoma and is preparing to undergo treatment.Which treatments may be used to treat this patient's cancer? (Select all that apply.)

A) Radiation
B) Bone marrow transplant
C) Chemotherapy
D) Lymph node transplant
E) Monoclonal antibody therapy

Question 9

In general,the best prognosis for long-term disease-free survival occurs with

A) ALL (acute lymphoid leukemia).
B) CLL (chronic lymphoid leukemia).
C) AML (acute myeloid leukemia).
D) CML (chronic myeloid leukemia).

Question 10

The Philadelphia chromosome is a balanced chromosome translocation that forms a new gene called

A) bcr-abl.
B) Rb.
C) p53.
D) ARA-c.

Question 11

A 5-year-old patient's parents report loss of appetite and fatigue in their child.The parents also state that the child refuses to walk as a result of pain.The child's most likely diagnosis is

A) ALL (acute lymphoid leukemia)
B) CLL (chronic lymphoid leukemia)
C) AML (acute myeloid leukemia)
D) CML (chronic myeloid leukemia)

Question 12

The patient is a 12-year-old boy diagnosed with acute lymphoid leukemia (ALL).As part of treatment,the patient must undergo several weeks of chemotherapy.The most serious complication of chemotherapy is

A) vomiting.
B) anemia.
C) alopecia.
D) infection.

Question 13

What is the correct definition of complete remission (CR)of leukemia?

A) CR is the absence of leukemic cells in the blood.
B) CR is less than 5% blasts in marrow and normal CBC values.
C) CR is absence of leukemic cells regardless of CBC values.
D) CR is less than 5% leukemic cells in the blood.

Question 14

A diagnostic laboratory finding in myeloma is

A) Bence Jones proteins in the urine.
B) decreased platelet count.
C) increased IgM antibody titer.
D) elevated blood glucose levels.

Question 15

Which form of leukemia demonstrates the presence of the Philadelphia chromosome?

A) ALL (acute lymphoid leukemia)
B) CLL (chronic lymphoid leukemia)
C) AML (acute myeloid leukemia)
D) CML (chronic myeloid leukemia)

Question 16

Which viruses have been implicated as cancer-causing agents? (Select all that apply.)

A) Epstein-Barr
B) Human T-cell leukemia
C) Human immunodeficiency
D) Herpes
E) Shingles

Question 17

The patient is a 12-year-old boy with acute lymphoblastic leukemia (ALL).Manifestations of the patient's leukemia prior to treatment may include (Select all that apply.)

A) anemia.
B) leukocytosis.
C) leukopenia.
D) thrombocytopenia.
E) anuria.

Question 18

A patient is diagnosed with stage IIA Hodgkin disease.This patient's clinical stage was most likely determined by (Select all that apply.)

A) patient history.
B) lymph node biopsy.
C) laparotomy results.
D) CT scan.
E) physical examination.

Question 19

The major cause of death from leukemic disease is

A) infection.
B) malnutrition.
C) hypovolemic shock.
D) kidney failure.

Question 20

A patient is diagnosed with CML (chronic myeloid leukemia).The patient may experience which of these symptoms? (Select all that apply.)

A) Fatigue
B) Weight loss
C) Abdominal discomfort
D) Joint pain
E) Sweats

Question 21

Two of the most serious oncology emergencies associated with non-Hodgkin lymphoma are obstruction of the superior vena cava and compression of the spinal cord.

Question 22

A patient is diagnosed with hairy cell leukemia.The patient's laboratory results would most likely indicate a decrease in (Select all that apply.)

A) granulocytes.
B) platelets.
C) white blood cells.
D) red blood cells.
E) melanocytes.

Question 23

The only known curative treatment for CML is allogeneic bone marrow transplantation from a suitable donor.

Question 24

A patient is diagnosed with myeloma.The nurse teaches the patient about the multiple tumor sites that can develop with this cancer.The possible tumor sites in myeloma include the (Select all that apply.)

A) liver.
B) spleen.
C) stomach.
D) pancreas.
E) kidneys.