Deck 16: Over the Counter Analgesics

Question 1

Which form of cyclooxygenase is involved in normal cellular maintenance, particularly in the stomach and kidneys?

A)COX-1
B)COX-2
C)COX-3
D)COX-4

Answer 1

COX-1

Question 2

Which of the following does NOT have anti-inflammatory action?

A)Acetaminophen
B)Aspirin
C)Ibuprofen
D)Naproxen

Answer 2

Acetaminophen

Question 3

Which of the following analgesics are NOT advised for use by patients with a history of any of the symptoms of the "aspirin triad," unless under the supervision of a physician?

A)Acetaminophen
B)Lithium
C)Ibuprofen
D)Naproxen

Answer 3

Naproxen

Question 4

What over-the-counter analgesic is usually suggested for people with hypertension?

A)Acetaminophen
B)Aspirin
C)Ibuprofen
D)Naproxen

Question 5

What is the most frequently used medicinal compound in the world?

A)Antihistamine
B)Acetaminophen
C)Ibuprofen
D)Aspirin

Question 6

Naproxen's value in treating heart attacks .

A)is apparently very limited
B)is slower to appear than are the effects of aspirin
C)is about the same as aspirin's
D)requires co-administration of morphine

Question 7

The most commonly used agent for the control of fever around the world is .

A)naproxen
B)ibuprofen
C)aspirin
D)acetaminophen

Question 8

Scientists have discovered that low doses of are effective as an adjunctive treatment for transient ischemic attacks (TIAs).

A)naproxen
B)aspirin
C)acetaminophen
D)morphine

Question 9

The full anti-inflammatory effects of ibuprofen .

A)appear just as rapidly as those of aspirin
B)are more rapidly achieved than those of aspirin
C)require 3 days to begin to appear
D)require 2-4 weeks of use to appear

Question 10

The use of aspirin in the treatment of myocardial infarction is most effective .

A)if consumed in high doses
B)if consumed in low doses
C)when used with a diuretic agent
D)when initiated in the first 48 hours of the attack

Question 11

Acetaminophen is as potent as aspirin, but can be toxic to the liver.As such, doses greater than are not recommended except when under the care of a physician.

A)2,000 mg for 3 days
B)6,000 mg for 5 days
C)4,000 mg for 10 days
D)1,000 mg for 1 week

Question 12

A single dose of two 325 aspirin tablets provides the same level of analgesia as .

A)5 milligrams of Demerol®
B)15 milligrams of Demerol®
C)100 mg of codeine
D)50 milligrams of meperidine

Question 13

Aspirin, in rare cases, can contribute to all but which of the following?

A)Depression
B)Cataracts
C)Reye's syndrome
D)Hepatotoxicity

Question 14

Acetaminophen's analgesic potential is approximately .

A)twice that of aspirin
B)equal to that of aspirin
C)a quarter that of aspirin
D)50% higher than that of aspirin

Question 15

At the dosage levels suggested for ibuprofen as an over-the-counter agent (325-650 mg every 4 hours), this compound's analgesic effects are .

A)twice that of aspirin
B)equal to that of aspirin
C)a quarter that of aspirin
D)50% higher than aspirin's analgesic potential

Question 16

Salicin _.

A)shares the unpleasant gastric side effects of its chemical cousin, salicylic acid
B)is less irritating to the stomach than acetylsalicylic acid
C)is about as irritating to the stomach than acetylsalicylic acid
D)was introduced in 1898 as an analgesic by Bayer Pharmaceuticals

Question 17

There is evidence that regular low-dose aspirin use is associated with possible prevention of all of the following EXCEPT _.

A)cataracts
B)Crohn's disease
C)diabetic retinopathy
D)esophageal and ovarian cancer

Question 18

Aspirin doses as low as mg a day can significantly increase the user's risk for ulcers or bleeding in the gastrointestinal tract.

A)25
B)50
C)75
D)100

Question 19

Which of the following over-the-counter analgesics are responsible for more than 100,000 overdoses each year, the majority being unintentional?

A)Acetaminophen
B)Aspirin
C)Ibuprofen
D)Naproxen

Question 20

It has been estimated that the annual worldwide production of aspirin is about doses each year, a quarter of which is consumed in the United States.

A)500 million
B)100 billion
C)500 billion
D)700 million

Question 21

How does aspirin differ for narcotic analgesics in treating pain?

Question 22

How can aspirin be both good and bad for the circulatory system?

Question 23

The perception that over-the counter drugs are safe can potentially result in serious consequences.

Question 24

To be fully effective in an acetaminophen overdose, N-acetylcysteine must be administered within 3 hours of the time the overdose was ingested.

Question 25

Discuss the possible effects of an overdose of acetaminophen.

Question 26

Cumulative dose toxicity from acetaminophen can develop after just 10 days of use at recommended dosage levels.

Question 27

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) lists four different diagnoses related to the misuse of OTC analgesic medications.

Question 28

Like the NSAIDs, acetaminophen interferes with blood clotting.

Question 29

Trace the development of aspirin from the earlier discovery of salicin, noting some of the problematic effects of the various compounds that emerged on the way to the discovery of aspirin.

Question 30

Describe some of the potential complications seen with OTC analgesic use.