Deck 8: Gene Therapy and Pharmacogenomics

Question 1

The nurse is asking a patient about his drug history, and the patient states, "Whenever I take any strong pain medications, I usually sleep for hours. I have no idea why that happens!" The nurse considers that which of these is true about this patient's statement?

A) The patient is exaggerating about a normal side effect of pain medications.
B) The patient's reaction to pain medications may point to a difference in his ability to metabolize certain drugs.
C) The patient will need higher doses of medication for pain control.
D) The patient should never receive strong pain medications.

Answer 1

The patient's reaction to pain medications may point to a difference in his ability to metabolize certain drugs.

Question 2

The nurse is discussing gene therapy in a continuing education class. Which is the best definition of eugenics?

A) The use of gene therapy to prevent disease
B) The development of new drugs based on gene therapy
C) Intentional selection, before birth, of genotypes that are considered more desirable than others
D) The determination of genetic factors that influence a person's response to medications

Answer 2

Intentional selection, before birth, of genotypes that are considered more desirable than others

Question 3

The nurse is reviewing the applications of gene therapy. Which drug is manufactured as a result of indirect gene therapy?

A) Vitamin K
B) Warfarin
C) Human insulin
D) Heparin

Answer 3

Human insulin

Question 4

The nurse is performing an assessment of a patient. Which assessment findings may indicate a higher risk for genetic disorders?

A) The patient's father was diagnosed with heart disease at 60 years of age.
B) The patient's mother was diagnosed with breast cancer at 33 years of age.
C) The patient's grandfather died of a cerebral vascular accident at 78 years of age.
D) The patient's sister has a history of both renal and lung cancer.
E) The patient has two uncles and a grandparent who have been diagnosed with Alzheimer's disease.

Question 5

The nurse is explaining the Human Genome Project to colleagues. Which of these is the main purpose of the Human Genome Project?

A) The study of genetic diseases.
B) The study of genetic traits in humans.
C) The discovery new genetic diseases.
D) To describe the entire genome of a human being.

Question 6

A patient will be receiving ranitidine (Zantac) 150 mg twice a day. A liquid form is ordered because the patient cannot swallow pills or capsules; the concentration of the liquid is 15 mg/mL. How many milliliters will the patient receive per dose?

Question 7

The nurse is preparing a class on gene therapy for a group of students. Which statements about gene therapy are true?

A) The FDA must review and approve all human clinical genetic trials.
B) Gene therapy may involve creating new genes within a human.
C) Gene therapy may involve replacing a mutated gene with a healthy copy of the gene.
D) Some trials involve introducing a new gene into the body to help fight disease.
E) Gene therapy may include inactivating a mutated gene that is not functioning properly.

Question 8

The nurse is reviewing principles of genetics. Which of these is a long strand of DNA that is contained within the nuclei of cells?

A) Gene
B) Allele
C) Genome
D) Chromosome

Question 9

A patient has just been told that she has the genetic markers for a severe type of breast cancer. After the patient meets with the physician, the patient's daughter asks the nurse, "What did the doctor tell my mother? She seems upset." What is the nurse's best response?

A) "I'm sorry, but I'm not allowed to discuss that."
B) "The physician will discuss this with you."
C) "It seems that your mother has the genetic markers for a type of breast cancer."
D) "This is information that your mother will need to discuss with you."

Question 10

The nurse is asking a patient about his family history as part of an assessment. Which component is included in an effective family history?

A) Asking the patient about the current and past health status of the patient's children
B) Covering at least three generations of family history
C) Obtaining a family history of the patient's spouse
D) Asking about the family history for the patient's siblings and parents only