Deck 15: Over the Counter Analgesics

Question 1

Aspirin interferes with blood clotting.

Answer 1

True

Question 2

The perception that over-the counter drugs are safe can potentially result in serious consequences.

Answer 2

True

Question 3

What is the most frequently used compound in the world?

A) Antihistamine
B) Acetaminophen
C) Ibuprofen
D) Aspirin

Answer 3

Aspirin

Question 4

What over-the-counter analgesic is usually suggested for people with hypertension?

A) Acetaminophen
B) Aspirin
C) Ibuprofen
D) Naproxen

Question 5

A single dose of aspirin (325 mg) provides the same level of analgesia as

A) 5 milligrams of Demerol®.
B) 15 milligrams of Demerol®.
C) 100 mg of codeine.
D) 50 milligrams of meperidine.

Question 6

Salicin

A) shares the harsh gastrointestinal side effects of its chemical cousin, salicylic acid.
B) is less irritating to the stomach than acetylsalicylic acid.
C) is about as irritating to the stomach than acetylsalicylic acid.
D) was introduced in 1898 as an analgesic by Bayer Pharmaceuticals.

Question 7

Doses of acetaminophen higher than are toxic to the liver.

A) 2,000 mg in 24 hours
B) 6,000 mg in 24 hours
C) 4,000 mg in 24 hours
D) 1,000 mg in 24 hours

Question 8

The anti-inflammatory effects of ibuprofen

A) appear just as rapidly as those of aspirin.
B) are more rapidly achieved than those of aspirin.
C) require 3 days to begin to appear.
D) require 2-4 weeks of use to appear.

Question 9

Aspirin, in rare cases, can contribute to which of the following?

A) Depression
B) Hepatoxicity
C) Reye's syndrome
D) All of these answers

Question 10

The most commonly used agent for the control of fever around the world is

A) naproxen.
B) ibuprofen.
C) aspirin.
D) acetaminophen.

Question 11

At the dosage levels suggested for ibuprofen as an over-the-counter agent (200-400 mg every 4 hours), this compound's analgesic effects are

A) twice that of aspirin.
B) equal to that of aspirin.
C) a quarter that of aspirin.
D) 50 percent higher than aspirin's analgesic potential.

Question 12

Which of the following analgesics are NOT advised for use by patients with a history of gastrointestinal bleeding, unless ordered by a physician?

A) Acetaminophen
B) Aspirin
C) Ibuprofen
D) Naproxen

Question 13

The use of aspirin in the treatment of myocardial infarction is most effective

A) if consumed in high doses.
B) if consumed in low doses.
C) when used with a diuretic agent.
D) when initiated in the first 48 hours of the attack.

Question 14

There is evidence that regular low dose aspirin use is associated with possible prevention of all of the following EXCEPT

A) myocardial infarctions.
B) hemophilia.
C) breast cancer.
D) ovarian cancer.

Question 15

Acetaminophen's analgesic potential is approximately

A) twice that of aspirin.
B) equal to that of aspirin.
C) a quarter that of aspirin.
D) 50 percent higher than that of aspirin.

Question 16

An antipyretic would be most helpful in treating

A) stomach pain.
B) a headache.
C) a fever.
D) a swollen knee.

Question 17

Which of the following does NOT have anti-inflammatory action?

A) Acetaminophen
B) Aspirin
C) Ibuprofen
D) Naproxen

Question 18

It has been estimated that the annual worldwide consumption of aspirin is doses.

A) 500 million
B) 50 billion
C) 500 billion
D) 700 million

Question 19

Which of the following over-the-counter analgesics are responsible for more than 100,000 overdoses each year, the majority being unintentional?

A) Acetaminophen
B) Aspirin
C) Ibuprofen
D) Naproxen

Question 20

Which form of cyclooxygenase is required for normal body regulation?

A) COX-1
B) COX-2
C) COX-3
D) None of the above

Question 21

How does aspirin differ for narcotic analgesics in treating pain?

Question 22

According to your text, more than 50 percent of acetaminophen overdoses are

A) unintended.
B) attempts at suicide.
C) intentional.
D) made by males.

Question 23

Cumulative dose toxicity from acetaminophen

A) does not develop when used as directed.
B) can develop after just 10 days of use at recommended dosage levels.
C) does require that another protein bound substance be administered.
D) requires 10 days of constant use at higher-than-recommended dosage levels.

Question 24

Discuss the possible effects of an overdose of acetaminophen.

Question 25

Aspirin is thought to be a factor in of bleeding ulcers.

A) 10-20 percent
B) 40-50 percent
C) 20-41 percent
D) 8-12 percent

Question 26

Naproxen's value in treating heart attacks

A) is apparently either nonexistent or very limited.
B) is slower to appear than are the effects of aspirin.
C) is about the same as aspirin's.
D) requires co-administration of morphine.

Question 27

Why would your textbook even include a chapter on over­the­counter (OTC) analgesics?

Question 28

Describe some of the potential complications seen with OTC analgesic use.

Question 29

How can aspirin be both good and bad for the circulatory system?

Question 30

To be fully effective in an acetaminophen overdose, N-acetylysteine must be administered within of the time the overdose was ingested.

A) 12 hours
B) 24 hours
C) 72 hours
D) 96 hours