Deck 19: Drugs for the Treatment of Other Endocrine Disorders

Question 1

Exophthalmos is a characteristic sign of

A)cretinism.
B)hyperthyroidism.
C)acromegaly.
D)dwarfism.
E)hyperprolactinemia.

Answer 1

hyperthyroidism.

Question 2

Why do postmenopausal women use medroxyprogesterone (Provera)in conjunction with estrogens?

A)It potentiates estrogen and postmenopausal women require a higher amount.
B)It prevents an increase in the risk of uterine cancer that can occur when estrogen is used alone.
C)It facilitates the passage of estrogen across membrane surfaces.
D)It helps to prevent osteoporosis.

Answer 2

It prevents an increase in the risk of uterine cancer that can occur when estrogen is used alone.

Question 3

What causes ovulation on day 14 of the menstrual cycle?

A)An increase in the rate of secretion of FSH and LH
B)A decrease in the rate of secretion of FSH and LH
C)The release of large quantities of estrogen
D)The release of large quantities of progesterone

Answer 3

An increase in the rate of secretion of FSH and LH

Question 4

Which of the following statements is characteristic of diffuse toxic goiter?

A)It is also known as Plummer disease.
B)It is characterized by a diffusely enlarged,highly vascular thyroid gland.
C)It occurs primarily in older patients and usually arises from long-standing nontoxic goiter.
D)Both A and B are characteristics.
E)Both B and C are characteristics.

Question 5

Estrogens are used to treat menstrual disturbances such as uterine bleeding.Estrogen is also used to reduce the symptoms of menopause.

A)Both statements are true.
B)Both statements are false.
C)The first statement is true;the second statement is false.
D)The first statement is false;the second statement is true.

Question 6

The major female sex hormone(s)is (are) (1)estrogen, (2)androgen, (3)progestin.

A)1,2,3
B)1,2
C)2,3
D)1,3
E)1 only

Question 7

Synthetic analogs of vasopressin are used to: (1)treat pituitary diabetes insipidus, (2)treat hemophilia A and von Willebrand disease, (3)induce labor and postpartum lactation, (4)control postpartum hemorrhage.

A)1,2,3,4
B)1,2,3
C)2,3,4
D)1,2
E)3,4

Question 8

Simple goiter is prevalent in some areas of the world because iodine is abundant in most foods.

A)Both the statement and the reason are correct.
B)The statement is correct,but the reason is not.
C)The statement is not correct,but the reason is correct.
D)Neither the statement nor the reason is correct.

Question 9

Which of the following is used in infertility cases to stimulate ovarian follicle development?

A)Follicle-stimulating hormone (FSH)
B)Luteinizing hormone (LH)
C)Human chorionic gonadotropin (hCG)
D)Human menopausal gonadotropin (hMG)

Question 10

The posterior pituitary secretes

A)prolactin.
B)oxytocin.
C)corticotrophin-releasing hormone.
D)All of the above
E)None of the above

Question 11

Hypopituitarism can produce

A)goiter.
B)acromegaly.
C)diabetes insipidus.
D)giantism.

Question 12

Which female hormone promotes egg maturation?

A)Follicle-stimulating hormone (FSH)
B)Luteinizing hormone (LH)
C)Estrogen
D)Progesterone
E)Chorionic gonadotropin

Question 13

Which of the following statements is true of progesterone during the normal female sexual cycle?

A)Progesterone secretion declines if implantation does not occur by the end of the menstrual cycle.
B)If implantation takes place,the developing trophoblast secretes chorionic gonadotropin,which sustains the corpus luteum,thus maintaining progesterone and estrogen levels.
C)Progesterone stimulates uterine contractility.
D)Both A and B are true.
E)Both B and C are true.

Question 14

Cretins exhibit all of the following dental abnormalities except which one?

A)Malocclusion
B)Large teeth
C)Delayed tooth eruption
D)Increased tendency to develop periodontal disease

Question 15

Leuprolide is used to treat

A)hyperthyroidism.
B)diabetes.
C)fertility problems.
D)hypothyroidism.

Question 16

Which of the following glands is also called the "master gland"?

A)Thyroid gland
B)Anterior pituitary gland
C)Pituitary gland
D)Gonads

Question 17

Increases in estrogen and progestin levels are associated with which oral lesion?

A)Aphthous stomatitis
B)Caries
C)Gingivitis
D)Increased tooth mobility
E)Lichen planus

Question 18

The increase in gingival inflammation may occur even with a decrease in the amount of plaque.This circumstance may be a result of increased levels of prostaglandin E (PGE),estradiol,and progesterone in the saliva.

A)Both statements are true.
B)Both statements are false.
C)The first statement is true;the second statement is false.
D)The first statement is false;the second statement is true.

Question 19

Which of the following is usually the drug of choice for treatment of hyperthyroidism in patients older than 21 years?

A)Propylthiouracil
B)Methimazole
C)Radioactive iodide (131I)
D)Propranolol

Question 20

Which of the following anterior pituitary hormones are involved in the female menstrual cycle: (1)thyroid-stimulating hormone (TSH), (2)adrenocorticotropic hormone (ACTH), (3)follicle-stimulating hormone (FSH), (4)luteinizing hormone (LH)?

A)1,2,3,4
B)1,2
C)1,3
D)2,3
E)3,4

Question 21

Which of the following medications is indicated for the palliative treatment of advanced breast cancer in postmenopausal women?

A)Clomiphene
B)Leuprolide
C)Tamoxifen
D)Danazol

Question 22

Which of the following conditions is a contraindication for the use of oral contraceptives?

A)Chronic obstructive pulmonary disease
B)Type II diabetes
C)Carcinoma of the breast
D)Splenectomy

Question 23

Thyroid hormones are synthesized from tyrosine and

A)calcium.
B)sodium.
C)potassium.
D)iodine.
E)iron.

Question 24

No treatment should be initiated for any patient with a visible goiter,exophthalmos,or a history of taking antithyroid drugs until approval is obtained from the patient's physician.

Question 25

Which type of food contains high levels of iodine?

A)Green vegetables
B)Yellow vegetables
C)Beef
D)Citrus fruit
E)Seafood

Question 26

Which of the following agents is used for the treatment of cancer of the prostate?

A)Methyltestosterone
B)Clomiphene
C)Finasteride
D)Tamoxifen
E)Mifepristone

Question 27

Hormonal contraceptives have the potential to cause or aggravate gingival inflammation.

Question 28

Which drug is administered to induce ovulation in a patient being treated for infertility?

A)Human menopausal gonadotropin (hMG)
B)Human chorionic gonadotropin (hCG)
C)Luteinizing hormone (LH)
D)Follicle-stimulating hormone (FSH)

Question 29

Hormones from the opposite sex are often used to manage prostate,breast,and uterine cancers.

Question 30

In most homeostatic systems the hormone released has a negative feedback effect on the secretion of the hormone-stimulating substance.

Question 31

The anterior lobe of the pituitary gland secretes growth hormone.

Question 32

Each of the following is a potential consequence of hypersecretion of pituitary hormones except one.Which is the exception?

A)Goiter
B)Acromegaly
C)Diabetes insipidus
D)Cushing disease
E)Giantism

Question 33

Some antibiotics are thought to reduce the effectiveness of hormonal contraceptives by

A)preventing absorption across the membrane surface of the enteric plexus.
B)suppressing intestinal flora.
C)chelation to form insoluble byproducts.
D)forcing progesterone levels to be maintained.

Question 34

The medical use of bromocriptine (Parlodel)is to

A)stimulate pituitary function.
B)inhibit pituitary function.
C)stimulate thyroid function.
D)inhibit thyroid function.

Question 35

All of the following are side effects associated with oral contraceptives except which one?

A)Blood clot
B)Weight gain
C)Headache
D)Nausea
E)Anorexia

Question 36

Which of the following agents is categorized as a schedule III controlled substance?

A)Medroxyprogesterone
B)Tamoxifen
C)RU-486
D)Nandrolone
E)Danazol

Question 37

Which drug is used to treat symptoms of menopause and postmenopausal osteoporosis?

A)Clomiphene
B)Leuprolide
C)Tamoxifen
D)Danazol
E)Raloxifene

Question 38

Synthetics analogs of vasopressin,a posterior pituitary hormone,may be used to treat diabetes.

Question 39

Which pituitary hormone is used to treat diabetes insipidus?

A)Menotropin (Pergonal)
B)Oxytocin (Pitocin,Syntocinon)
C)Vasopressin (Pitressin)
D)Bromocriptine (Parlodel)

Question 40

Estrogen therapy may promote endometrial carcinoma in postmenopausal women.