Deck 8: Gastrointestinal Drugs

Question 1

All of the drugs and substances below irritate the mucous membranes and can cause an ulcer,EXCEPT ________.

A) aspirin
B) NSAIDs
C) antiemetic drugs
D) alcohol and caffeine

Answer 1

antiemetic drugs

Question 2

Which of the following is NOT an area where a peptic ulcer can form?

A) duodenum
B) esophagus
C) colon
D) stomach

Answer 2

colon

Question 3

Chloride channel laxative drugs,such as lubiprostone (Amitiza),stimulate chloride channels in the mucosa of the intestinal wall.This causes ________.

A) the release of hydrochloric acid in the stomach
B) a "bandage" to form over a gastric ulcer
C) fluid to flow into the intestines to soften the stool
D) lipase in the diet to be excreted in the stool rather than absorbed

Answer 3

fluid to flow into the intestines to soften the stool

Question 4

Proton pump inhibitor drugs can be used to treat all of the following GI diseases,EXCEPT ________.

A) GERD
B) peptic ulcers
C) obesity
D) H. pylori infections

Question 5

GERD is treated with ________.

A) antacid drugs
B) appetite suppressant drugs
C) H₂ blocker drugs
D) A and C

Question 6

Which of the following statements is FALSE?

A) H₂ blocker drugs block histamine receptors on the parietal cells of the stomach.
B) The parietal cells of the stomach release H. pylori.
C) The parietal cells of the stomach release hydrochloric acid.
D) H₂ blocker drugs block the action of histamine on receptors.

Question 7

The generic drug 5-aminosalicylic acid ________.

A) decreases intestinal inflammation by blocking the production of hydrochloric acid
B) decreases intestinal inflammation by blocking the production of prostaglandins
C) increases intestinal peristalsis by blocking the production of hydrochloric acid
D) decrease intestinal peristalsis by blocking the production of prostaglandins.

Question 8

Which drug acts topically on the actual surface of the ulcer,forming a protective layer or "bandage" that allows a peptic ulcer to heal?

A) esomeprazole (Nexium)
B) lorcaserin (Belviq)
C) Helidac
D) sucralfate (Carafate)

Question 9

Appetite suppressant drugs are also known as ________ drugs.

A) proton pump inhibitor
B) absorbent
C) antacid
D) anorexiant

Question 10

Anticholinergic drugs block the action of acetylcholine and this ________.

A) decreases the rate of peristalsis in the intestine
B) stimulate the rate of peristalsis to move food through the intestine
C) absorbs excess water from the intestine
D) stimulate the release of hydrochloric acid in the stomach

Question 11

All of the following are bulk-producing laxative drugs,EXCEPT ________.

A) Fiberall
B) Metamucil
C) Mylanta
D) FiberCon

Question 12

Antacid drugs are weak ________.

A) acids that exert a therapeutic effect by neutralizing hydrochloric acid
B) acids that exert a therapeutic effect by neutralizing pepsin
C) bases that exert a therapeutic effect by neutralizing hydrochloric acid
D) bases that exert a therapeutic effect by neutralizing pepsin

Question 13

The suffix -tidine is common to generic ________ drugs.

A) antacid
B) antidiarrheal
C) H₂ blocker
D) stool softener laxative

Question 14

Which category of laxative drug has the most natural and safest action?

A) bulk-producing laxative drugs
B) chloride channel laxative drugs
C) osmotic laxative drugs
D) stool softener laxative drugs

Question 15

Antidiarrheal drugs produce a therapeutic effect by ________.

A) absorbing extra water from diarrhea stools
B) slowing the frequency of contractions (peristalsis) in the intestines
C) absorbing extra water from diarrhea stools or slowing peristalsis in the intestines
D) using osmotic pressure to attract water into the stool

Question 16

Successful treatment of an H.pylori infection involves the use of a combination of drugs that include all of the following,EXCEPT ________.

A) An antibiotic/antiprotozoal drug
B) a bismuth drug
C) a proton pump inhibitor drug
D) an antacid drug

Question 17

Gastric stimulant drugs increase the frequency of gastric emptying and are used to treat ________.

A) gastroesophageal reflux disease
B) constipation
C) H. pylori infection
D) obesity

Question 18

A drawback to the use of the antacid drugs sodium bicarbonate,Alka-Seltzer,and baking soda is their ________.

A) ineffectiveness
B) high cost
C) high sodium content
D) inability to neutralize acid

Question 19

Which of the following can irritate the intestinal mucosa and stimulate the chemoreceptor trigger zone and vomiting center in the brain.

A) antiemetic drugs
B) chemotherapy drugs
C) hydrochloric acid
D) laxative drugs

Question 20

All of the following trade names are antiemetic drugs used to treat motion sickness,EXCEPT ________.

A) Qsymia
B) Dramamine
C) Antivert
D) Transderm-Scop

Question 21

The suffix -prazole is common to generic ________.

A) proton pump inhibitor drugs
B) appetite suppressant drugs
C) antacid drugs
D) bulk-producing laxative drugs

Question 22

Which of the following antidiarrheal drugs contains the Schedule III narcotic drug opium?

A) paregoric
B) Pepto-Bismol
C) bismuth
D) Lomotil

Question 23

Which of the following statements is TRUE?

A) Proton pump inhibitor drugs are used to treat diarrhea.
B) The proton pump is located in the intestine.
C) Proton pump inhibitor drugs are the drug of choice for appetite suppression and weight loss.
D) The proton pump is an enzyme system that produces hydrochloric acid.

Question 24

A unique characteristic of Transderm-Scōp is that it is ________.

A) the first FDA-approved weight loss drug
B) worn as a patch behind the ear
C) effective for both heartburn and motion sickness
D) given orally

Question 25

All of the following are 5-aminosalicylic acid drugs used to treat ulcerative colitis,EXCEPT ________.

A) mesalamine (Asacol, Lialda, Pentasa, Rowasa)
B) balsalazide (Colazal)
C) sulfasalazine (Azulfidine)
D) loraserin (Belviq)

Question 26

All of the following are proton pump inhibitor drugs,EXCEPT ________.

A) Lomotil
B) Prilosec
C) Nexium
D) Prevacid

Question 27

Janie Wallace is taking an appetite suppressant drug.She should be aware of which of these statements?

A) Appetite suppressant drugs should be used in conjunction with dietary restrictions.
B) Appetite suppressant drugs should be taken only on a short-term basis.
C) Patients may develop drug dependence and experience withdrawal symptoms if the drugs are discontinued abruptly.
D) all of the above

Question 28

Di-Gel,Gelusil,and Rolaids are all examples of ________.

A) H₂ blocker drugs
B) irritant laxative drugs
C) combination antacid drugs
D) antiemetic drugs

Question 29

Which of the following statements is FALSE?

A) Zantac is available in a 150 mg dose both as a prescription drug and as an OTC drug.
B) The HB in Tagamet HB stands for histamine blocker.
C) The AC in Pepcid AC stands acid control or may refer to the Latin phrase ante cibum.
D) An over-the-counter drug can be purchased without a prescription and is safe for consumers to use if the directions are followed.

Question 30

Which of the following statements is TRUE?

A) The weight loss drug Alli can cause fatty stools that pass involuntarily.
B) The prescription drug Xenical contains the same drug as the over-the-counter drug Alli.
C) Alli belongs to the lipase inhibitor category of drugs.
D) all of the above

Question 31

All of the following are laxative drugs EXCEPT ________.

A) milk of magnesia
B) Perdiem
C) lubiprostone (Amitiza)
D) mesalamine (Asacol, Lialda)

Question 32

Which of the following statements is FALSE?

A) Simethicone is available as an individual drug or in combination with antacid drugs.
B) Simethicone is used to treat flatulence and gas.
C) Simethicone changes the surface tension of air bubbles trapped in the GI tract.
D) Simethicone is used to treat diarrhea.

Question 33

The trade name of the generic drug cimetidine is ________.

A) Nexium
B) Pepcid
C) Amitiza
D) Tagamet

Question 34

All of the following are H₂ blocker drugs,EXCEPT ________.

A) Zantac
B) Pepcid
C) Transderm-Scōp
D) Axid

Question 35

All of the following categories of drugs are used to treat Crohn's disease,EXCEPT ________.

A) monoclonal antibody drugs
B) corticosteroid drugs
C) antispasmodic drugs
D) appetite suppressant drugs

Question 36

Gastric stimulant drugs ________.

A) are used to treat GERD
B) include metoclopramide (Reglan)
C) increase the frequency of gastric emptying
D) all of the above

Question 37

All of the following can contribute to peptic ulcer formation,EXCEPT ________.

A) aspirin and nonsteroidal anti-inflammatory drugs
B) antibiotic drugs
C) the use of alcohol
D) the use of caffeine

Question 38

Another trade name for the laxative drug docusate (Colace)is ________.

A) Surfak
B) Antivert
C) Qsymia
D) Tums

Question 39

Cimetidine is the generic name for the trade name drug ________.

A) Maalox
B) Nexium
C) opium
D) Tagamet

Question 40

Which of the following is a combination drug that contains an anti-infective drug (bismuth),an antibiotic drug (tetracycline),and an antiprotozoal drug (metronidazole)and is used to treat H.pylori infection of the stomach?

A) Xenical
B) Helidac
C) AcipHex
D) Tums

Question 41

Ulcerative colitis is a chronic disease of the esophagus and stomach.

Question 42

The drug category of antacid drugs contains each of the following as an active ingredient,EXCEPT ________.

A) calcium carbonate
B) attapulgite
C) aluminum hydroxide
D) magnesium hydroxide.

Question 43

The generic drug lubiprostone,a chloride channel activator drug used to treat irritable bowel syndrome,is related to the well-known trade name drug ________.

A) Tagamet
B) Antivert
C) Amitiza
D) Mylanta

Question 44

A drug that blocks a receptor (such as an H₂ blocker drug)is known as an antagonist drug.

Question 45

Lipase inhibitor drugs chemically bond to the enzyme lipase to improve its ability to break down dietary fat in the intestines.

Question 46

Anticholinergic drugs are used to treat diarrhea because they slow the frequency of peristalsis in the intestines.

Question 47

All of the following statements are true,EXCEPT ________.

A) Helicobacter pylori are helical (spiral) bacteria.
B) Helicobacter pylori have flagella (thin, whip-like tails).
C) Helicobacter pylori are the cause of some gastric ulcers.
D) Helicobacter pylori infections are treated with lipase inhibitor drugs.

Question 48

Besides being used to treat H.pylori infections in gastric ulcers,what other disease is the generic drug metronidazole used to treat?

A) acne rosacea of the facial skin
B) vaginal bacteriosis
C) pelvic inflammatory disease
D) all of the above

Question 49

Simethicone relieves gas trapped in the GI tract because of its action as an antacid drug.

Question 50

Cimetidine (Tagamet)was the first H₂ blocker prescription drug to be approved by the FDA for over-the-counter use.

Question 51

All peptic ulcers begin with irritation of the mucous membranes caused by hydrochloric acid.

Question 52

Irritable bowel syndrome,characterized with cramping and diarrhea alternating with constipation,is treated with all of the following categories of drugs EXCEPT ________.

A) antianxiety drugs
B) antacid drugs
C) antispasmodic drugs
D) antidiarrheal drugs and laxative drugs

Question 53

Narcotic drugs are most commonly used for pain relief,but have a common side effect of causing constipation which is used as the therapeutic effect in treating diarrhea.

Question 54

Patients taking appetite suppressant drugs for obesity may develop dependence and withdrawal symptoms if these drugs are discontinued abruptly,because these are Schedule III and Schedule IV drugs.

Question 55

Which of the following trade names are NOT related to the generic drug mesalamine that is used to treat ulcerative colitis?

A) linaclotide (Linzess)
B) Asacol
C) Pentasa
D) Rowasa

Question 56

Patients who are actively vomiting and cannot take oral drugs can be given antiemetic drugs in the form of a rectal suppository.

Question 57

The drug 5-aminosalicylic acid and topical corticosteroid drugs are both used to treat ulcerative colitis,but 5-aminosalicylic acid can treat severe inflammation because it has a powerful anti-inflammatory effect.

Question 58

The trade name AciPhex refers to the drug's effect on the acid content and pH level of the stomach.

Question 59

The ending -tidine is common to generic H₂ blocker drugs.

Question 60

Appetite suppressant drugs for obesity are chemically related to amphetamine drugs,but are less addictive than amphetamine drugs.

Question 61

The use of calcium-containing antacid drugs is a good way for women to get the calcium they need in their diets.

Question 62

The prescription drug Antivert to treat vertigo takes the anti- part of its name from the word antibiotic,which shows its drug action.

Question 63

Stool softener laxative drugs act as emulsifiers that allow fat and water to mix together to soften the stool.

Question 64

A GI cocktail is given to a patient who has a bleeding peptic ulcer.

Question 65

GERD occurs when stomach acid flows back into the esophagus causing irritation,inflammation,and pain.The abbreviation GERD stands for ________.

Question 66

The abbreviation MOM stands for the generic antacid drug name ________.

Question 67

The final step in acid production in the gastric parietal cell involves a structure known as the proton pump.

Question 68

Diarrhea can be caused by a bacterial infection due to the bacterium Helicobacter pylori.

Question 69

Dulcolax as a liquid is the generic drug magnesium hydroxide,but Dulcolax as an enteric-coated tablet or suppository is the generic drug bisacodyl.

Question 70

Simethicone is often included in combination antacid drugs because it relieves flatulence and breaks up air bubbles trapped in the GI tract.

Question 71

The ending -mab is common to ________ drugs.

Question 72

Histamine is released in the stomach,where it stimulates the production of hydrochloric acid.

Question 73

Peptic ulcers in the stomach are specifically known as ________ ulcers.

Question 74

The over-the-counter weight loss drug Alli contains the same drug as the prescription weight-loss drug Xenical,but at a lower dose.

Question 75

A patient with a bleeding ulcer is immediately given an intravenous antacid drug in the emergency room.

Question 76

Consumers think of weight-loss drugs as being safe and free of side effects,and they are.

Question 77

The antidiarrheal drug attapulgite is an absorbent drug that contains an aluminum-magnesium compound taken from clay soil.

Question 78

________ drugs are used to control the nausea and vomiting that is associated with many different diseases.

Question 79

The AR in the trade name Axid AR stands for anti-reflux.

Question 80

The endings -salamine,-salazide,and -salazine are common to generic 5-aminosalicyclic acid drugs.