Deck 27: Anticoagulants and Coagulants

Question 1

The low-molecular-weight heparins produce _____ activity when compared with standard heparin due to _____.

A) Less, differences in chemical structure
B) Less, slower absorption
C) More, differences in chemical structure
D) More, slower absorption

Answer 1

Less, differences in chemical structure

Question 2

Combining aspirin and ibuprofen would _____ overall antiplatelet effects because _____.

A) Decrease, ibuprofen interferes with aspirin's inactivation of COX-1 enzyme
B) Increase, ibuprofen interferes with aspirin's inactivation of COX-1 enzyme
C) Decrease, aspirin interferes with ibuprofen's inactivation of COX-1 enzyme
D) Increase, aspirin interferes with ibuprofen's inactivation of COX-1 enzyme

Answer 2

Decrease, ibuprofen interferes with aspirin's inactivation of COX-1 enzyme

Question 3

The irreversible process by which aspirin inactivates cyclooxygenase production is:

A) Thromboxane levels are elevated by aspirin.
B) Prostacyclin levels are elevated by aspirin.
C) Platelets lack a nucleus and can't produce more cyclooxygenase.
D) Platelet enzymes are inhibited by aspirin.

Answer 3

Platelets lack a nucleus and can't produce more cyclooxygenase.

Question 4

A hospital patient with a tendency to form blood clots is in the recovery room after having hip replacement surgery.Which anticoagulant would best serve the patient's needs?

A) Warfarin
B) Aspirin
C) Heparin
D) Streptokinase

Question 5

Standard heparin is preferred for pregnant patients needing an anticoagulant because:

A) Molecular size will allow it to cross the placenta to help the offspring.
B) The offspring will receive the full anticoagulant effect.
C) Molecular size will not allow it to cross the placenta to affect the offspring.
D) The offspring will receive only a partial anticoagulant effect.

Question 6

The preferred anticoagulant during pregnancy is:

A) Heparin
B) Warfarin
C) Streptokinase
D) Enoxaparin

Question 7

A patient experiencing hemorrhaging after receiving heparin should be given:

A) Vitamin K
B) Protamine sulfate
C) Aspirin
D) Streptokinase

Question 8

Why would a patient currently experiencing thromboembolisms be given warfarin?

A) To prevent future platelet aggregation
B) To prevent primary thromboembolic complications
C) To prevent secondary thromboembolic complications
D) To prevent hemorrhaging

Question 9

Toxicity from oral anticoagulants and other medications can often occur because of:

A) Enhanced metabolism in the liver
B) Reduced clearance from the kidneys
C) Enhanced plasma protein binding by the oral anticoagulant
D) Plasma protein binding displacement

Question 10

In arterial thrombosis or deep vein thrombosis,platelets will _____ production of _____.

A) Increase, prostacyclin
B) Increase, thromboxane
C) Decrease, prostacyclin
D) Decrease, thromboxane

Question 11

One disadvantage of cellulose hemostatic sponges compared to gelatin sponges would be:

A) Thrombocytopenia
B) Agranulocytosis
C) Anaphylactic shock
D) Bone regeneration interference

Question 12

What are the two groups in which heparin can be classified?

A) Standard heparin and low-molecular-weight heparin
B) Standard heparin and high-molecular-weight heparin
C) Low-molecular-weight heparin and high-molecular-weight heparin
D) Low-molecular-weight heparin and fractionated heparin

Question 13

The primary reason heparin cannot be administered orally is that:

A) The mucopolysaccharide is too large to be absorbed in the intestines.
B) The mucopolysaccharide is destroyed by gastric acid in the stomach.
C) The peptide is too large to be absorbed in the intestines.
D) The peptide is destroyed by gastric acid in the stomach.

Question 14

Patients on oral anticoagulant therapy should be monitored by which tests?

A) PTT or APTT
B) INR or APTT
C) Protime (PT) or APTT
D) Protime (PT) or INR

Question 15

The formation of _____ practically guarantees the clotting cascade to proceed.

A) Clotting factor VIII
B) Vitamin K
C) Stuart factor
D) Thromboplastin

Question 16

The mechanism of action for which medication works by converting plasminogen to plasmin?

A) Aspirin
B) Alteplase
C) Enoxaparin
D) Heparin

Question 17

Patients with a tendency to develop blot clots have a problem with which regulatory process?

A) Hematopoiesis
B) Leukopoiesis
C) Hemostasis
D) Hemopoiesis

Question 18

The presence of _____ can occur from overactive clotting activity in the body that is not properly regulated.

A) Glycosilated hemoglobin
B) Thromboembolisms
C) Thrombocytopenia
D) Anemia

Question 19

Which anticoagulant's mechanism of action involves an inhibition of platelet aggregation?

A) Heparin
B) Warfarin
C) Streptokinase
D) Aspirin

Question 20

What are the first cells or cell components to reach a site of injury to initiate coagulation?

A) Thrombocytes
B) Erythrocytes
C) Monocytes
D) Leucocytes