Question 1

Genes in the family are of particular interest due to their ability to degrade pharmaceuticals.&#10;A)cytochrome P450&#10;B)CYP2D6&#10;C)Glutathione S-transferease&#10;D)SNP

Accepted Answer

Cytochrome P450 enzymes are responsible for metabolizing a wide range of drugs and other xenobiotics in the body, including certain pharmaceuticals. Some members of this gene family are specifically known to be involved in drug metabolism and are therefore of particular interest in pharmacology and toxicology.

Question 2

The exon trapping method for determining eukaryotic coding sequences relies on .&#10;A)flanking splice recognition sites,which are used during RNA processing&#10;B)complementary DNA that is produced prior to exon trapping&#10;C)both the promoter and polyA)tail recognition sequences&#10;D)the presences of restriction enzyme recognition sequences

Accepted Answer

The exon trapping method relies on flanking splice recognition sites, which are used during RNA processing. This allows for the isolation of coding sequences and helps to identify intron-exon boundaries. The method involves inserting a genomic fragment upstream of a reporter gene and screening for gene expression, which can only occur if the genomic fragment contains a coding sequence that can be spliced into the reporter mRNA. Therefore, the correct answer is A.

Question 3

Which of the following makes up more percentage of the human genome than the others listed in the answer choices?&#10;A)protein coding genes&#10;B)LINEs&#10;C)heterochromatin&#10;D)introns

Accepted Answer

D

Question 4

Escherichia coli have approximately genes.&#10;A)1,000&#10;B)4,000&#10;C)10,000&#10;D)25,000

Accepted Answer

Escherichia coli has around 4,000 genes in its genome.

Question 5

In some metagenomic analyses,organisms in the community do not have to be cultured.

Accepted Answer

Metagenomics allows for the characterization of complex microbial communities without the need for culturing individual organisms. Instead, the genetic material of all microorganisms in a sample can be analyzed, even those that are difficult to culture or have never been cultured.

Question 6

Sequence tagged sites are needed when genomes .&#10;A)contain mostly coding sequence&#10;B)contain mostly non-coding sequence&#10;C)are very tiny&#10;D)have many repetitive sequences

Accepted Answer

The answer of Sequence tagged sites are needed when genomes...

Question 7

Eukaryotic cell lines,usually rodents,that contain chromosomal fragments from other eukaryotic species are called .&#10;A)transfected hybrids&#10;B)artificial chromosomes&#10;C)radiation hybrids&#10;D)STS/EST cell lines

Accepted Answer

Eukaryotic cell lines that contain chromosomal fragments from other species are known as radiation hybrids, generated by irradiating the cells to induce chromosomal breakage followed by fusion with rodent cells to create a stable hybrid. Transfected hybrids involve introducing foreign DNA into a cell line, artificial chromosomes are DNA constructs used for cloning large segments of DNA, while STS/EST cell lines contain short sequences from expressed genes.

Question 8

Correlating individual genotypes with drug treatment is called .&#10;A)genomics&#10;B)pharmacogenetics&#10;C)pharming&#10;D)pharmacogenomics

Accepted Answer

Correlating individual genotypes with drug treatment is called pharmacogenomics. This field studies how genetic variations can affect an individual's response to a drug and how these variations can be used to personalize treatment.

Question 9

The genomes of some plants and a few protozoa have more genes than humans.

Accepted Answer

It is true that some plants and protozoa have more genes than humans. For example, the Japanese plant Paris japonica has about 50% more genes than humans. The protozoan Amoeba dubia has about 200 times more genes than humans.

Deck 9: Genomics Systems Biology