Deck 9: Blood and Hemopoiesis

Question 1

A patient with acute myeloblastic leukemia might have a very high bone marrow concentration of

A) neutrophilic myelocytes
B) basophilic myelocytes
C) eosinophilic myeloblasts
D) colony-forming unit erythrocytes
E) neutrophilic stab cells

Answer 1

C

Question 2

A pediatrician sees a child with hereditary deficiency of NADPH oxidase. This child is

A) anemic
B) unable to bind IgE to his basophils and mast cells
C) unable to fight parasitic worm invaders
D) subject to persistent infections
E) unable to mount a humorally mediated immune response

Answer 2

D

Question 3

Erythroblastosis fetalis is a condition that may be fatal to the newborn because of

A) Rh blood group
B) A blood group
C) B blood group
D) M blood group
E) N blood group

Answer 3

A

Question 4

Which of the following white blood cells give rise to macrophages?

A) monocytes
B) lymphocytes
C) neutrophils
D) basophils
E) eosinophils

Question 5

Human erythrocytes do not have mitochondria but can produce ATP because these cells possess

A) carbonic anhydrase
B) chloride shift
C) band 3 proteins
D) spectrin
E) a glycolytic pathway

Question 6

A patient dies from saddle embolism. This is due to a blood clot in the

A) coronary artery
B) coronary sinus
C) bifurcation of the common carotid artery
D) bifurcation of the pulmonary artery
E) bifurcation of the abdominal aorta

Question 7

A patient with high corticosteroid levels would be expected to have

A) normal blood eosinophil count
B) low blood eosinophil count
C) high T cell count
D) low T cell count
E) high B cell count

Question 8

A patient whose plasma $\gamma$ -globulin levels are highly elevated

A) has a high colloid osmotic pressure
B) is in the process of a humorally mediated immune reaction
C) is in the process of a cellularly mediated immune reaction
D) is immunosuppressed
E) has a viral infection

Question 9

A patient with a high eosinophil blood count most probably

A) has a parasitic worm invasion
B) suffers from spherocytosis
C) does not have an allergic reaction
D) has a low erythrocyte count
E) has a high erythrocyte count

Question 10

A patient whose colloid osmotic pressure is 15 mm Hg or less but has a normal blood volume is lacking

A) $\gamma$ -globulins
B) $\alpha$ -globulins
C) $\beta$ -globulins
D) albumins
E) fibrinogen

Question 11

A patient with sickle cell anemia has a point mutation in which the amino acid valine is incorporated into the chain instead of

A) glutamate
B) tyrosine
C) glycine
D) proline
E) lysine

Question 12

Which of the following components of blood is not manufactured by the liver?

A) albumins
B) $\alpha$ -globulins
C) $\beta$ -globulins
D) $\gamma$ -globulins
E) fibrinogen

Question 13

A patient with vitamin K deficiency has normal levels of

A) prothrombin
B) factor VII
C) factor IX
D) factor X
E) fibrinogen

Question 14

A patient presents at the emergency department in Yosemite National Park with gastrointestinal problems. He was camping and drank water from a clear spring without treating it first. His complaints include foul-smelling flatulence and diarrhea, bloating, and nausea. The emergency department physician suspects a Giardia infection because Giardia lamblia is endemic in the rivers and streams of the region. The patient's blood sample should show an elevated levels of

A) erythrocytes
B) neutrophils
C) basophils
D) eosinophils
E) monocytes

Question 15

In a healthy patient, the most populous leukocytes are

A) monocytes
B) lymphocytes
C) basophils
D) eosinophils
E) neutrophils

Question 16

Patients with secondary polycythemia have

A) low levels of erythropoietin
B) higher than normal levels of neutrophils
C) a decreased blood viscosity
D) higher than normal erythrocyte levels
E) lower than normal platelet levels

Question 17

A patient has hereditary spherocytosis. This condition is due to a defective

A) hemoglobin A₁
B) substitution of valine for glutamate
C) impaired formation of $\beta$ -chains of the hemoglobin molecule
D) abnormal spectrin molecule
E) abnormal band 3 molecule

Question 18

A 65-year-old patient living in Florida sees his physician in early June complaining of generalized weakness, constant tiredness, and lack of energy. A complete blood count shows smaller than normal erythrocytes and lowered hemoglobin concentration. The patient also suffers from angular stomatitis, glossitis, and reduction in the number of lingual papillae. The physician should be considering which of the following possibilities?

A) iron deficiency anemia
B) aplastic anemia
C) blood loss
D) seasonal affective disorder
E) depression

Question 19

The structures at the tip of the arrow

A) arise from CFU-GM
B) arise from reticulocytes
C) house major dense protein
D) house $\alpha$ -granules
E) release von Willebrand factor

Question 20

A second-year surgical resident is found dead in his car in the garage of his townhouse with the engine still running. He left the hospital after a 24-hour shift, drove his car into his garage, and apparently fell asleep and succumbed to carbon monoxide poisoning. CO transformed his hemoglobin to the

A) F hemoglobin
B) T^- hemoglobin
C) A₁ hemoglobin
D) A₂ hemoglobin
E) R^- hemoglobin

Question 21

The cell at the tip of the arrow is a(n)

A) basophilic metamyelocyte
B) basophilic myelocyte
C) neutrophilic myelocyte
D) eosinophilic metamyelocyte
E) eosinophilic myelocyte

Question 22

Which of the following cells is derived from colony-forming unit granulocyte-macrophage (CFU-GM)?

A) monocyte
B) basophil
C) erythrocyte
D) T cell
E) eosinophil

Question 23

The cell at the tip of the arrow is a(n)

A) eosinophilic metamyelocyte
B) neutrophilic metamyelocyte
C) basophilic metamyelocyte
D) promyelocyte
E) myeloblast

Question 24

The cell at the arrow tip is a

A) basophilic erythroblast
B) myeloblast
C) proerythroblast
D) promyelocyte
E) polychromatophilic erythroblast

Question 25

The cell indicated by the arrow is a

A) neutrophil
B) neutrophilic metamyelocyte
C) eosinophilic metamyelocyte
D) eosinophilic myelocyte
E) promyelocyte

Question 26

The cell at the tip of the pointer

A) phagocytoses bacteria
B) phagocytoses antigens
C) releases major basic protein
D) releases eosinophil chemotactic factor
E) binds IgE to its plasmalemma

Question 27

The cell at the tip of the arrow is a

A) lymphocyte
B) basophilic erythroblast
C) promonocyte
D) polychromatophilic erythroblast
E) orthochromatophilic erythroblast

Question 28

The cell at the tip of the arrow is a(n)

A) basophilic metamyelocyte
B) basophilic myelocyte
C) neutrophilic myelocyte
D) eosinophilic metamyelocyte
E) eosinophilic myelocyte

Question 29

The cell at the tip of the arrow is a

A) basophilic erythroblast
B) myeloblast
C) proerythroblast
D) promyelocyte
E) polychromatophilic erythroblast