Deck 27: Population Genetics

Question 1

Which of the following is not true concerning a population in equilibrium according to the Hardy-Weinberg rule?

A) There is no migration into or out of the population
B) Individuals of the population mate randomly
C) The population size is very large
D) Selection is favoring the dominant allele
E) There is no mutation in the populations

Answer 1

D

Question 2

If the allele frequency of the dominant allele is 0.4, what value is used for the term p2 in the equation p2 + 2pq + q2 = 1?

A) 0.4
B) 0.2
C) 0.16
D) 16

Answer 2

C

Question 3

In a given population of Drosophila, curly wings (c) is recessive to the wild-type condition of straight wings (c+). You isolate a population of 35 curly winged flies, 70 flies that are heterozygous for straight wings and 45 that are homozygous for straight wings. What is the frequency of alleles in this population?

A) 35% c; 45% c+
B) 46.7% c; 53.3% c+
C) 50% c; 50% c+
D) 55% c; 45% c+
E) The frequencies cannot be calculated from the provided information

Answer 3

B

Question 4

The inbreeding coefficient (F) tells us what about an individual?

A) The probability that they are homozygous due to inheritance from a common ancestor
B) Their genotype
C) The probability of obtaining a certain allele from the gene pool

Question 5

The degree of relatedness of two members of a pedigree is calculated using ________.

A) the calculation of average heterozygosity
B) the Hardy-Weinberg rule
C) the inbreeding coefficient
D) the chi-square test

Question 6

The formula p2 + 2pq + q2 = 1 is associated with which of the following?

A) Calculations of heterozygosity
B) Hardy-Weinberg equilibrium
C) Calculations of recombination frequencies
D) Degrees of freedom

Question 7

Migration of a random few individuals from one population to a new area to establish a new population is an example of ________

A) Bottleneck effect
B) Mutation
C) Founder effect
D) Selection

Question 8

The characteristics of a given population over time are ________.

A) Dynamic
B) Static

Question 9

In this equation p2 + 2pq + q2 = 1, what does the term 2pq represent?

A) The genotype frequency of homozygous recessive individuals
B) The genotype frequency of homozygous dominant individuals
C) The genotype frequency of heterozygous individuals
D) The sum of the phenotype frequencies in the population

Question 10

In humans, the gene for eye color is an example of a ________ trait.

A) Monomorphic
B) Polymorphic

Question 11

A group of individuals from the same species that occupy the same region and can interbreed with one another is the definition of a ________.

A) Species
B) Population
C) Race
D) Community
E) Kingdom

Question 12

Which of the following types of selection favors the survival of individuals with the intermediate phenotype?

A) Disruptive selection
B) Stabilizing selection
C) Directional selection

Question 13

Most natural populations are in a state of equilibrium according to Hardy-Weinberg.

Question 14

Which of the following types of selection favors one extreme of a phenotypic distribution?

A) Disruptive selection
B) Stabilizing selection
C) Directional selection

Question 15

Which of the following factors would result in the allele frequency of a population not adding up to 1.0, as is the case in the Hardy-Weinberg rule?

A) Genetic drift
B) Inbreeding
C) A population changing due to selection
D) None of the answers, the allele frequencies must always equal 1.0

Question 16

Genetic drift has a greater influence on ________ populations.

A) Small
B) Large
C) It affects both equally

Question 17

In a given population of Drosophila, curly wings (c) is recessive to the wild-type condition of straight wings (c+). You isolate a population of 35 curly winged flies, 70 flies that are heterozygous for straight wings and 45 that are homozygous for straight wings. What is the total number of alleles in the gene pool?

A) 2
B) 150
C) 230
D) 300
E) 140

Question 18

Which of the following is true regarding a balanced polymorphism?

A) The frequency of alleles is not changing over time
B) The homozygous condition for the alleles is not advantageous to the organism
C) An example in humans is sickle-cell anemia
D) All of the answers are correct

Question 19

Which of the following will alter the frequency of alleles in the population the least?

A) Mutation
B) Natural selection
C) Genetic drift
D) Migration
E) All of the answers are equal

Question 20

If two individuals of a population, who vary in their phenotype, preferentially mate, it is called ________.

A) Outbreeding
B) Inbreeding
C) Negative assortative mating
D) Positive assortative mating

Question 21

Human society favors outbreeding, or the mating of individuals that are genetically unrelated.

Question 22

The smallest difference in DNA sequence between a gene in two individuals is a single-nucleotide polymorphism (SNP).

Question 23

A gene that is found in less that 1% of a given population is called monomorphic.

Question 24

Migration is a key evolutionary mechanism by which microevolution occurs.

Question 25

The accumulation of new mutations in a population is usually a ________ factor against the fitness of the population.

A) Negative
B) Positive
C) Neutral

Question 26

The measure of the reproductive success of a genotype is called Darwinian fitness.

Question 27

The probability that a gene will be altered by a mutation is called the mutation rate.

Question 28

The selection coefficient is the measure to which a phenotype is selected against.

Question 29

The prevalence of the allele for sickle cell anemia in some populations is an example of?

A) Heterogeneous environments
B) Balancing selection
C) Inverted selection
D) Non-Darwinian selection
E) Nonrandom mating

Question 30

The movement of alleles from one population to another is called population flow.

Question 31

Which of the following is NOT a characteristic by which a population is in equilibrium according to Hardy-Weinberg equation?

A) The population is large.
B) There is no migration into or out of the population.
C) There is no selection against a given genotype.
D) There is no mutation in the gene being studied.
E) There is nonrandom mating

Question 32

In the calculation of Hardy-Weinberg equilibria in the context of nonrandom mating, random mating is represented by the factor f equal to 1.

Question 33

Mutations are the only source of genetic variation in a population.

Question 34

A SNP would best be described as ________.

A) A gene that comes in multiple different alleles
B) A balanced polymorphism system
C) A single nucleotide difference between two DNA sequences
D) The most likely mutation to affect protein function

Question 35

The allele pool is the sum of all of the alleles in a population.

Question 36

Which of the following is NOT a step to calculate a coefficient of inbreeding?

A) Determine the mutation rate.
B) Determine the total number of common ancestors.
C) Determine the shortest inbreeding path between the individual and the common ancestor.
D) Calculate the inbreeding path for each common ancestor.
E) Place values in the inbreeding coefficient formula.

Question 37

Which type of selection would lead to two distinct phenotypes?

A) Stabilizing selection
B) Phenotype selection
C) Fitness selection
D) Disruptive selection
E) Directional selection

Question 38

At equilibrium the allele and genotype frequencies of a population change over time.

Question 39

Random genetic drift is due to chance events that alter the allele frequency in a population.

Question 40

New genetic variation in a population is a critical aspect of microevolution.

Question 41

Horizontal gene transfer between individuals in a population, while not a mutation, is a source of genetic variation.

Question 42

Horizontal gene transfer is limited to between prokaryotic bacteria of the same species.

Question 43

You are preparing to perform DNA fingerprinting by PCR for the first time. Select the reagent that would result in complications in the interpretation of your results.

A) PCR primers that anneal to the repetitive region of the microsatellites
B) PCR primers that anneal to regions flanking the microsatellites
C) Human DNA
D) Taq polymerase

Question 44

In a certain population, the frequency of allele A is 0.3 and the frequency of allele a is 0.7. The population inbreeds such that f = 0.1. What is the frequency of each genotype in the population?

A) AA: 0.09, Aa: 0.42, aa: 0.49
B) AA: 0.49, Aa: 0.42, aa: 0.09
C) AA: 0.01, Aa: 0.90, aa: 0.09
D) AA: 0.111, Aa: 0.378, aa: 0.511
E) AA: 0.21, Aa: 0.42, aa: 0.37

Question 45

In exon shuffling, the duplicated or rearranged exons appear as new domains in different genes.