Deck 34: Treatment of Infections Ii: Antiviral Drugs

Question 1

In people infected with HIV,highly active antiretroviral therapy (HAART)typically consists of:

A)one reverse transcriptase inhibitor at maximal dosage.
B)one protease inhibitor at maximal dosage.
C)two drugs,usually a reverse transcriptase inhibitor plus a protease inhibitor.
D)two drugs,usually a nonnucleoside reverse transcriptase inhibitor plus a nucleoside reverse transcriptase inhibitor.
E)three drugs,usually two reverse transcriptase inhibitors plus a protease inhibitor.

Answer 1

three drugs,usually two reverse transcriptase inhibitors plus a protease inhibitor.

Question 2

Viral infections are often more difficult to treat than other types of infections because:

A)viruses contain organelles (ribosomes,mitochondria,etc. )that are naturally resistant to antiviral drugs.
B)virus particles are much larger than other infectious microorganisms such as bacteria.
C)viruses penetrate into human cells and cannot be killed easily without harming the human cell.
D)all of the above
E)none of the above

Answer 2

viruses penetrate into human cells and cannot be killed easily without harming the human cell.

Question 3

Reverse transcriptase inhibitors such as zidovudine [Retrovir],didanosine [Videx],and zalcitabine [Hivid] are especially important for physical therapists because they may cause side effects such as:

A)peripheral neuropathy.
B)myopathy.
C)joint pain.
D)all of the abov
E)none of the above

Answer 3

all of the abov

Question 4

Certain anti-HIV drugs (e.g. ,zidovudine [Retrovir],didanosine [Videx],zalcitabine [Hivid])are known as reverse transcriptase inhibitors because they:

A)prevent adsorption/penetration of HIV into T4 lymphocytes.
B)inhibit transcription of viral RNA to viral DNA.
C)inhibit insertion of viral DNA into host-cell chromosomes.
D)all of the above
E)none of the above

Question 5

An antiviral vaccine is typically created by:

A)combining several antiviral drugs in the same pill.
B)administering a single,strong antiviral drug just after the onset of infection.
C)administering a single,strong antiviral drug at the peak of the viral infection.
D)administering drugs that suppress the immune response to viral infection.
E)none of the above

Question 6

Interferons are small proteins that:

A)exert nonspecific antiviral activity.
B)control cell differentiation.
C)limit excessive cell proliferation.
D)modify certain immune processes
E)all of the above