Which of the following statements about warfarin (Coumadin) is NOT true?
A) It actively breaks down the fibrin network, thereby dissolving formed thrombi.
B) It helps treat chronic atrial fibrillation.
C) It prevents coagulation by antagonizing the effects of vitamin K.
D) It was originally used as rat poison.

Question

Quizplus · Accepted Answer

Warfarin (Coumadin) does not actively break down the fibrin network to dissolve formed thrombi. It works by preventing the formation of new thrombi by antagonizing the effects of vitamin K, which is necessary for the production of various clotting factors. Warfarin is commonly used to prevent stroke and systemic embolism in patients with chronic atrial fibrillation. It was originally used as rat poison but was eventually discovered to have medical benefits in preventing blood clots.

Which of the Following Statements About Warfarin (Coumadin) Is NOT