In cirrhosis, how does cholesterol alter the fluidity of the plasma membrane of erythrocytes?
A) Cholesterol decreases the membrane fluidity of the erythrocyte, which reduces its ability to carry oxygen.
B) Cholesterol decreases the membrane fluidity of erythrocytes, which reduces its ability to carry hemoglobin.
C) Cholesterol increases the membrane fluidity of erythrocytes, which allows binding of excess glucose.
D) Cholesterol increases the membrane fluidity of erythrocytes, which prolongs its life span beyond 120 days.

Question

Quizplus · Accepted Answer

Cholesterol reduces the fluidity of the plasma membrane of erythrocytes, making it more rigid. This can decrease the ability of erythrocytes to deform and pass through small vessels, reducing their ability to carry oxygen. In cirrhosis, accumulation of cholesterol in the liver can lead to increased levels in the plasma, which can alter the fluidity of erythrocyte membranes.

In Cirrhosis, How Does Cholesterol Alter the Fluidity of the Plasma