The multiple-hit model of cancer means that

Question

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The multiple-hit model of cancer suggests that multiple mutations are necessary for cancer to develop, rather than a single mutation. This is because cancer cells need to accumulate various mutations in order to develop the ability to proliferate uncontrollably, invade surrounding tissues, spread to distant sites, evade the immune system, and survive adverse conditions such as chemotherapy or radiation therapy. These mutations can occur in a variety of genes that control cell growth and division, DNA repair, apoptosis, angiogenesis, and other cellular processes. Therefore, the likelihood of developing cancer increases with age and exposure to carcinogens or other risk factors that can damage DNA and increase the mutation rate. However, not all mutations lead to cancer, as the body has various mechanisms to detect and repair them, or eliminate the cells that carry them. Therefore, cancer is a complex and multifactorial disease that can result from a combination of genetic, environmental, and lifestyle factors.

The Multiple-Hit Model of Cancer Means That