The rate-determining step of an E1_cb elimination is the deprotonation step.

Question

Quizplus · Accepted Answer

In an E1_cb elimination reaction, the deprotonation step is the slowest, or rate-determining, step. This is because the leaving group has already left in the previous step, and the formation of the pi bond occurs relatively quickly. Therefore, the rate of the reaction is primarily determined by how quickly the base can deprotonate the substrate to form the double bond.

The Rate-Determining Step of an E1cb Elimination Is the Deprotonation

The Rate-Determining Step of an E1_cb Elimination Is the Deprotonation