A client was recently admitted to the inpatient unit after a suicide attempt and has not responded to SSRIs or tricyclic antidepressants. The client asks the nurse, "Why can't monoamine oxidase inhibitors (MAOIs) be added to what I am on now?" Which response should the nurse make?

Question

Quizplus · Accepted Answer

Combining SSRIs or tricyclic antidepressants with monoamine oxidase inhibitors (MAOIs) can lead to a life-threatening condition called hypertensive crisis, which is a sudden and severe increase in blood pressure that can lead to organ damage or failure. Therefore, it is contraindicated to combine these medications. Electroconvulsive therapy (ECT) may be an option for some clients, but it is not the only option and should not be presented as the only option. It is important to give the client accurate information about their treatment options and potential risks.

A Client Was Recently Admitted to the Inpatient Unit After