Given that there are 200 V regions, 5 D regions, and 20 J regions for the heavy chain; 200 V regions for the kappa light chain and 5 J regions; and 4 subclasses of IgG, how many different specificities can be formed with the kappa light chain and the heavy chain given?

Question

Quizplus · Accepted Answer

The number of different specificities that can be formed is the product of the number of V regions, D regions, J regions, and subclasses. For the heavy chain, this is 200 x 5 x 20 x 4 = 8 x 10^7. For the kappa light chain, this is 200 x 5 = 1 x 10^3. Therefore, the total number of different specificities that can be formed is 8 x 10^7 x 1 x 10^3 = 8 x 10^10.

Given That There Are 200 V Regions, 5 D Regions