Suppose a research study shows that people who suffer from severe depression are homozygous for a mutation in the hypothetical DEP gene. Individuals without this form of depression have the following sequence at the beginning of the translated region of their DEP genes: 5'-ATG ACG TTT GAA ATT CAG TCT AGA-3' (Met Thr Phe Glu Ile Gln Ser Arg) . Affected individuals have the following sequence: 5'-ATG ACG TTT GAA ATT TAG TCT AGA-3'(Met Thr Phe Glu Ile STOP) . The mutation identified is most likely a:
A) missense mutation.
B) gain-of-function mutation.
C) nonsense mutatio
D) frameshift mutatio
E) deletio
Correct Answer:
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