In eukaryotic DNA, regions called "CpG islands" are often associated with unusual gene expression patterns, particularly decreased expression. What could be different about the DNA structure in these regions to account for decreased gene expression?

Question

Quizplus · Accepted Answer

Methylation of cytosine in CpG islands is associated with gene silencing, as it can inhibit the binding of transcription factors and attract proteins that compact the chromatin, leading to decreased gene expression.

In Eukaryotic DNA, Regions Called "CpG Islands" Are Often Associated