A 37- year- old Hispanic man who works in a chemical factory was seen because he was coughing u blood and experiencing chest pain. Laboratory results were as follows. What is the most likely diagnosis?

Complete blood count (CBC)—slight normocytic anemia; platelets and white blood cells within normal
limits
Urinalysis—3+ protein, 1+ blood
Renal function tests (BUN and creatinine)—elevated
Liver function tests—within normal limits
Electrolytes and glucose—within normal limits
Antinuclear antibody (ANA)—negative
Antimitochondrial antibody—negative
Antismooth muscle antibody—negative
Antiglomerular basement membrane antibody—positive

Question

A 37- year- old Hispanic man who works in a chemical factory was seen because he was coughing u blood and experiencing chest pain. Laboratory results were as follows. What is the most likely diagnosis?

Complete blood count (CBC)—slight normocytic anemia; platelets and white blood cells within normal
limits
Urinalysis—3+ protein, 1+ blood
Renal function tests (BUN and creatinine)—elevated
Liver function tests—within normal limits
Electrolytes and glucose—within normal limits
Antinuclear antibody (ANA)—negative
Antimitochondrial antibody—negative
Antismooth muscle antibody—negative
Antiglomerular basement membrane antibody—positive

Quizplus · Accepted Answer

The presence of antiglomerular basement membrane antibody, along with symptoms of coughing up blood (hemoptysis), chest pain, and the laboratory findings of renal impairment (elevated BUN and creatinine) and proteinuria, are characteristic of Goodpasture's syndrome.

A 37- Year- Old Hispanic Man Who Works in a Chemical