Plasma that contains antiphospholipids has prolonged clotting times in test tube assays. However, many patients with these antibodies experience an increased tendency to form blood clots.

Question

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Antiphospholipid antibodies interfere with the phospholipids involved in the clotting process, leading to prolonged clotting times in vitro. However, paradoxically, in vivo, they increase the risk of clot formation, contributing to conditions like antiphospholipid syndrome.

Plasma That Contains Antiphospholipids Has Prolonged Clotting Times in Test