For each of the three complement pathways, once C5 is split into C5a and C5b, formation of the membrane attack complex is identical for all three paths.

Question

Quizplus · Accepted Answer

After the cleavage of C5 into C5a and C5b, the subsequent steps leading to the formation of the membrane attack complex (MAC) are identical across the classical, lectin, and alternative complement pathways. This involves the assembly of C5b with C6, C7, C8, and multiple C9 molecules to form the MAC, which can create pores in the membrane of target cells, leading to cell lysis.

For Each of the Three Complement Pathways, Once C5 Is