In 1997, Dolly the sheep was cloned. Which of the following processes was used?
A) replication and dedifferentiation of adult stem cells from sheep bone marrow
B) separation of an early stage sheep blastula into separate cells, one of which was incubated in a surrogate ewe
C) transfer of an adult cell's nucleus into an enucleated sheep egg, followed by incubation in a surrogate
D) isolation of stem cells from a lamb embryo and production of a zygote equivalent

Question

Quizplus · Accepted Answer

Dolly the sheep was cloned using the process of somatic cell nuclear transfer (SCNT), which involved transferring the nucleus from an adult cell (in this case, a mammary gland cell) into an enucleated sheep egg (an egg cell with its own nucleus removed). The resulting egg was then implanted into a surrogate ewe's uterus and allowed to develop into a fetus. This technique allowed for the creation of a genetically identical animal to the adult donor, in this case, a sheep named Dolly.

In 1997, Dolly the Sheep Was Cloned