A sweat chloride test and CFTR mutation analysis performed in a 10-year-old child with signs and symptoms consistent with CF are inconclusive. Which of the following tests should the therapist suggest at this time?

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Quizplus · Accepted Answer

Measuring the difference in voltage potentials across the nasal epithelium is another method used in the diagnosis of CF, particularly when sweat chloride and CFTR mutation analysis results are inconclusive. However, the availability of this test remains limited, and it should only be performed at experienced centers.

A Sweat Chloride Test and CFTR Mutation Analysis Performed in a 10-Year-Old