A 15-year-old boy is complaining of severe headaches;he has a white count of 76.0 × 10⁹/L,platelet count of 55 × 10⁹/L,and a hematocrit of 33%.When a white cell differential is performed,most of the nucleated cells are blasts.They are CD2,CD4,and CD8 positive.The TdT marker is expressed.What is the most likely diagnosis?

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T-cell acute lymphoblastic leukemia is most often seen in teenage boys with a mediastinal mass,elevated peripheral blast counts,meningeal involvement,and infiltration of extra marrow sites.The blasts commonly mark as CD2,CD4,CD5,and CD8 positive.

A 15-Year-Old Boy Is Complaining of Severe Headaches;he Has a White