What effect do natriuretic peptides have during heart failure when the heart dilates?
A) Stimulates antidiuretic hormones.
B) Inhibits antidiuretic hormones.
C) Stimulates renin and aldosterone.
D) Inhibits renin and aldosterone.

Question

Quizplus · Accepted Answer

Natriuretic peptides inhibit renin and aldosterone during heart failure when the heart dilates.These make up a group of peptide hormones,including atrial natriuretic peptide (ANP),secreted from myocardial cells in the atria and brain natriuretic peptide (BNP)secreted from myocardial cells in the cardiac ventricles.When the heart dilates during volume expansion or heart failure,ANP and BNP inhibit sodium and water absorption by kidney tubules,inhibit the secretion of renin and aldosterone,vasodilate the afferent arterioles,and constrict the efferent arterioles.The result is increased urine formation,leading to decreased blood volume and blood pressure.

What Effect Do Natriuretic Peptides Have During Heart Failure When