Tay-Sachs disease is a human genetic disorder that results in cellular accumulation of very large, complex, undigested lipids. Which of the following organelles is most likely defective in Tay-Sachs disease?
A) the lysosome
B) the Golgi apparatus
C) the smooth endoplasmic reticulum
D) the rough endoplasmic reticulum

Question

Quizplus · Accepted Answer

Tay-Sachs disease is caused by a deficiency in the enzyme hexosaminidase A, which is necessary for breaking down certain lipids in the brain and nerve cells. This enzyme is found in the lysosomes, which are responsible for digesting cellular waste and recycling cellular components. Therefore, the lysosome is the organelle most likely defective in Tay-Sachs disease.

Tay-Sachs Disease Is a Human Genetic Disorder That Results in Cellular