What mid-20th Century event in Latin America caused the most economic and political concern for the United States?

Question

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The rise to power of Fidel Castro in Cuba caused the most economic and political concern for the United States in the mid-20th century. The U.S. had previously backed the regime of Fulgencio Batista, and Castro's communist government nationalized American-owned businesses in Cuba. This led to tensions between the U.S. and Cuba, including the failed Bay of Pigs invasion and the Cuban Missile Crisis. The U.S. placed a trade embargo on Cuba that still exists today.

What Mid-20th Century Event in Latin America Caused the Most