The observation that abnormal cleavage of mannose residues from glycoproteins causes an autoimmune disease in mice is most consistent with the role of which of the following structures in the normal immune response?
A)Cytoskeleton
B)Glycocalyx
C)Peroxisomes
D)Lysosomes
E)Microtubules

Question

Quizplus · Accepted Answer

The glycocalyx is a sugar-rich layer that surrounds cells and plays a role in cell-cell recognition and communication. It also contains glycoproteins that can trigger an immune response. Abnormal cleavage of mannose residues from glycoproteins suggests that the normal immune response involves recognition and response to specific glycoproteins, making option B the most consistent choice. The other structures listed, such as peroxisomes or microtubules, do not have a direct relationship with the immune response.

The Observation That Abnormal Cleavage of Mannose Residues from Glycoproteins