Which of the following is true in the context of interpreting the results of a case‐ control study compared to a cohort study? (select all that are true)
A)Exposure information has to be obtained after diagnosis of disease so may be less accurate than in a cohort study
B)Confounding is a bigger problem than in a cohort study
C)Accuracy of disease diagnosis is a bigger problem than in a cohort study
D)Recall bias is a bigger problem than in a cohort study
E)Confounding is less of a problem than in a cohort study

Question

Quizplus · Accepted Answer

In a case‐control study the exposure information is
collected after the development of disease and thus is often less accurate than in a
cohort study when it is collected before people develop disease.For example, it is
possible that an individual's exposure status may have changed with the onset of early
disease (e.g.they have lost weight or changed their diet), or that they will recall past
information differently because they know they have disease (recall bias).Confounding
(B, E) is a problem in all observational research and so is just as much a problem in
cohort studies as it is in case‐control studies.In a case‐control study it is usually possible
to verify the diagnosis of all cases so diagnosis is at least as accurate, if not more
accurate than in a cohort study (C).

Which of the Following Is True in the Context of Interpreting