A weak base is mostly excreted ___________.

Question

Quizplus · Accepted Answer

The uncharged base is lipophilic and will be reabsorbed.The charged form or base-H⁺ (R-NH₃⁺)is hydrophilic and will be excreted.If the urine is made alkaline,a lack of H⁺ in the urine moves the H⁺ from base-H⁺ and favors the uncharged base which is lipophilic - if the urine is acidic then lots of H⁺ force themselves on the base and cause base-H⁺ formation which is hydrophilic.The opposite holds true for weak acids.

A Weak Base Is Mostly Excreted ___________