Organic phosphorus insecticides are nerve poisons that work by binding to acetylcholinesterase and blocking the breakdown of acetylcholine.

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Organic phosphorus insecticides are known to bind irreversibly to acetylcholinesterase, which is an essential enzyme for the breakdown of acetylcholine, leading to accumulation of acetylcholine and eventually overstimulation of nerves and muscles, causing paralysis and death in insects.

Organic Phosphorus Insecticides Are Nerve Poisons That Work by Binding