Polyploidy may arise from the failure of chromosomes to separate during cell division or by the fertilization of an egg by more than one sperm.

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Polyploidy can occur due to nondisjunction, where chromosomes do not separate properly during cell division, or through mechanisms like polyspermy, where an egg is fertilized by multiple sperm, leading to an increase in the number of chromosome sets.

Polyploidy May Arise from the Failure of Chromosomes to Separate